Dental caries adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 10,885 adverse event reports that record the MedDRA preferred term Dental caries. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 599 reports in the 12 months to June 2026 and 441 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 1 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 108 drug pages with 25 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Dental caries name as a suspect product, in order of name
Drug	Class	Reports with this term
Abilify	Atypical antipsychotic	26
Acetaminophen Oxycodone Hydrochloride		33
Actemra	Interleukin-6 receptor antagonist	119
Actiq		133
Actonel	Bisphosphonate	100
Advair Diskus	Corticosteroid	30
Advair Diskus 100/50		51
Advair Hfa	Corticosteroid	32
Alendronate sodium	Bisphosphonate	162
Amlodipine Besilate		25
Aredia		234
Asacol		27
Atripla		119
Aubagio	Pyrimidine synthesis inhibitor	29
Avonex	Interferon beta	77
Belbuca	Partial opioid agonist	89
Benadryl	Histamine-1 receptor antagonist	37
Boniva		162
Buprenorphine	Partial opioid agonist	139
Buprenorphine Naloxone		207
Buprenorphine Transdermal Patch		31
Cabometyx	Kinase inhibitor	28
Cimzia	Tumor necrosis factor blocker	29
Ciprofloxacin	Fluoroquinolone antibacterial	40
Commit		52
Complera	Human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor	75
Cosentyx	Interleukin-17A antagonist	33
Crysvita		29
Diamicron		31
Dilaudid	Opioid agonist	101
Dupixent	Interleukin-4 receptor alpha antagonist	52
Duragesic-100		33
Eliquis	Factor Xa inhibitor	45
Enbrel	Tumor necrosis factor blocker	514
Fentanyl	Opioid agonist	54
Fentanyl citrate	Opioid agonist	30
Flovent	Corticosteroid	31
Forteo	Parathyroid hormone analog	110
Fosamax	Bisphosphonate	1,023
Fosamax Plus D		155
Gabapentin	Anti-epileptic agent	85
Gilenya	Sphingosine 1-phosphate receptor modulator	47
Gliclazide		36
Humira		620
Hydrocodone bitartrate and acetaminophen	Opioid agonist	124
Hydromorphone		27
Hydromorphone hydrochloride	Opioid agonist	38
Hydromorphone Tablets		25
Ibrance	Kinase inhibitor	51
Imbruvica	Kinase inhibitor	48
Infliximab	Tumor necrosis factor blocker	26
Jakafi	Janus kinase inhibitor	35
Kisqali	Kinase inhibitor	35
Lamictal	Anti-epileptic agent	36
Leflunomide	Antirheumatic agent	42
Lyrica		71
Methotrexate	Folate analog metabolic inhibitor	123
Morphine sulfate	Opioid agonist	95
MS Contin	Opioid agonist	63
Neurontin		25
Nexium	Proton pump inhibitor	28
Nicorette	Cholinergic nicotinic agonist	73
Nicotine	Cholinergic nicotinic agonist	27
Nicotine polacrilex	Cholinergic nicotinic agonist	57
Ocrevus	CD20-directed cytolytic antibody	74
Omeprazole	Proton pump inhibitor	28
Orencia	Selective T cell costimulation modulator	51
Oxycodone	Opioid agonist	29
Oxycodone and acetaminophen	Opioid agonist	92
Oxycodone hydrochloride	Opioid agonist	235
OxyContin	Opioid agonist	281
Oxyir		28
Ozempic	GLP-1 receptor agonist	25
Pegasys	Interferon alpha	39
Percocet	Opioid agonist	53
Plaquenil	Antimalarial	26
Pradaxa	Direct thrombin inhibitor	32
Prednisone	Corticosteroid	65
Prolia	RANK ligand inhibitor	481
Reclast	Bisphosphonate	50
Remicade	Tumor necrosis factor blocker	81
Revlimid	Thalidomide analog	113
Rinvoq	Janus kinase inhibitor	32
Rituxan	CD20-directed cytolytic antibody	73
Rituximab	CD20-directed cytolytic antibody	128
Seroquel	Atypical antipsychotic	66
Simponi	Tumor necrosis factor blocker	25
Soliris	Complement inhibitor	31
Strensiq		25
Stribild	Cytochrome P450 3A inhibitor	79
Suboxone	Opioid antagonist	639
Subutex		44
Tecfidera		39
Tiotropium bromide	Anticholinergic	52
Tramadol		60
Truvada	Human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor	161
Tysabri	Integrin receptor antagonist	140
Vicodin		36
Viread	Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	115
Vivitrol		36
Xarelto	Factor Xa inhibitor	49
Xeljanz	Janus kinase inhibitor	84
Xgeva	RANK ligand inhibitor	74
Xyrem	Central nervous system depressant	82
Zofran		29
Zoloft	Serotonin reuptake inhibitor	31
Zometa		471
Zubsolv	Opioid antagonist	31

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 53 pharmacologic classes with 25 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Dental caries name, in order of name
Class	Reports with this term
Angiotensin 2 receptor blocker	40
Angiotensin converting enzyme inhibitor	25
Anti-epileptic agent	155
Anticholinergic	80
Antimalarial	46
Antirheumatic agent	42
Aromatase inhibitor	45
Atypical antipsychotic	207
Benzodiazepine	46
beta-Adrenergic blocker	28
Bisphosphonate	1,363
Calcineurin inhibitor immunosuppressant	28
CD20-directed cytolytic antibody	294
Central nervous system depressant	97
Cholinergic nicotinic agonist	159
Complement inhibitor	31
Corticosteroid	283
Cytochrome P450 3A inhibitor	83
Direct thrombin inhibitor	32
Factor Xa inhibitor	102
Fluoroquinolone antibacterial	47
Folate analog metabolic inhibitor	146
GLP-1 receptor agonist	44
Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	122
Histamine-1 receptor antagonist	62
HMG-CoA reductase inhibitor	32
Human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor	242
Integrin receptor antagonist	156
Interferon alpha	39
Interferon beta	89
Interleukin-17A antagonist	46
Interleukin-4 receptor alpha antagonist	52
Interleukin-6 receptor antagonist	121
Janus kinase inhibitor	159
Kinase inhibitor	294
Nonsteroidal anti-inflammatory drug	28
Nucleoside analog antiviral	28
Nucleoside metabolic inhibitor	30
Opioid agonist	1,312
Opioid antagonist	705
Parathyroid hormone analog	117
Partial opioid agonist	276
Penicillin-class antibacterial	25
Proton pump inhibitor	76
Pyrimidine synthesis inhibitor	38
RANK ligand inhibitor	569
Selective T cell costimulation modulator	70
Serotonin and norepinephrine reuptake inhibitor	37
Serotonin reuptake inhibitor	90
Sphingosine 1-phosphate receptor modulator	49
Thalidomide analog	150
Tumor necrosis factor blocker	708
Vascular endothelial growth factor inhibitor	33

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Dental caries, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Dental caries
Age	Reports	Share
Under 2	20	0.2%
2 to 11	183	1.7%
12 to 17	85	0.8%
18 to 44	1,450	13.3%
45 to 64	2,572	23.6%
65 to 74	1,190	10.9%
75 and over	846	7.8%
Age not given	4,539	41.7%

Sex of the patient in the reports that record Dental caries
Sex	Reports	Share
Female	6,695	61.5%
Male	3,185	29.3%
Unknown or not given	1,005	9.2%

Age and sex are as the report gives them. 78.3% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Dental caries: adverse event reports that record this term. https://reportedreactions.com/reaction/dental-caries/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 1 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 1 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Oct 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Dental caries mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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