Acute respiratory failure adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 18,865 adverse event reports that record the MedDRA preferred term Acute respiratory failure. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 1,433 reports in the 12 months to June 2026 and 1,369 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 1 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 134 drug pages with 50 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Acute respiratory failure name as a suspect product, in order of name
Drug	Class	Reports with this term
Acetaminophen		113
Acetylsalicylic Acid		104
Adempas	Soluble guanylate cyclase stimulator	121
Advair Hfa	Corticosteroid	53
Aggrastat	Platelet aggregation inhibitor	92
Allopurinol	Xanthine oxidase inhibitor	66
Alprazolam	Benzodiazepine	67
Ambrisentan	Endothelin receptor antagonist	349
Amiodarone		105
Amlodipine	Calcium channel blocker	144
Apixaban	Factor Xa inhibitor	50
Aspirin	Nonsteroidal anti-inflammatory drug	182
Atezolizumab	Programmed death Receptor-1 blocking antibody	54
Atorvastatin		103
Avandia		81
Azacitidine	Nucleoside metabolic inhibitor	51
Azathioprine	Purine antimetabolite	60
Azithromycin	Macrolide antimicrobial	83
Baclofen	gamma-Aminobutyric acid-ergic agonist	69
Bamlanivimab		94
Bevacizumab	Vascular endothelial growth factor inhibitor	82
Bisoprolol	beta-Adrenergic blocker	76
Bortezomib	Proteasome inhibitor	51
Carboplatin	Platinum-based drug	240
Carfilzomib	Proteasome inhibitor	84
Casirivimab Imdevimab		59
Ceftriaxone	Cephalosporin antibacterial	67
Cisplatin	Platinum-based drug	184
Clopidogrel	P2Y12 platelet inhibitor	74
Clozapine	Atypical antipsychotic	135
Colchicine	Alkaloid	55
Cordarone		50
Coumadin		54
Cyclophosphamide	Alkylating drug	363
Cyclosporine	Calcineurin inhibitor immunosuppressant	149
Cytarabine	Nucleoside metabolic inhibitor	177
Daratumumab	CD38-directed cytolytic antibody	67
Dexamethasone	Corticosteroid	415
Diazepam	Benzodiazepine	69
Digoxin	Cardiac glycoside	66
Docetaxel	Microtubule inhibitor	58
Doxorubicin	Anthracycline topoisomerase inhibitor	165
Doxorubicin hydrochloride	Anthracycline topoisomerase inhibitor	80
Eliquis	Factor Xa inhibitor	123
Enbrel	Tumor necrosis factor blocker	82
Esbriet	Pyridone	76
Etoposide	Topoisomerase inhibitor	194
Everolimus	Kinase inhibitor	63
Fentanyl	Opioid agonist	120
Fludarabine	Nucleoside metabolic inhibitor	75
Fluorouracil	Nucleoside metabolic inhibitor	102
Fosamax	Bisphosphonate	68
Furosemide	Loop diuretic	115
Gabapentin	Anti-epileptic agent	85
Gemcitabine	Nucleoside metabolic inhibitor	73
Heparin		58
Heparin sodium	Anti-coagulant	56
Humira		205
Hydrocortisone	Corticosteroid	66
Hydroxychloroquine	Antimalarial	74
Ibuprofen	Nonsteroidal anti-inflammatory drug	66
Imbruvica	Kinase inhibitor	93
Infliximab	Tumor necrosis factor blocker	53
Ipilimumab	CTLA-4-directed blocking antibody	58
Jakafi	Janus kinase inhibitor	74
Keytruda	Programmed death Receptor-1 blocking antibody	121
Lasix	Loop diuretic	51
Lenalidomide	Thalidomide analog	124
Letairis	Endothelin receptor antagonist	127
Levofloxacin	Fluoroquinolone antibacterial	61
Linezolid	Oxazolidinone antibacterial	63
Lisinopril	Angiotensin converting enzyme inhibitor	96
Lorazepam	Benzodiazepine	95
Melphalan	Alkylating drug	78
Meropenem	Penem antibacterial	99
Metformin	Biguanide	145
Metformin hydrochloride	Biguanide	56
Methotrexate	Folate analog metabolic inhibitor	367
Methylprednisolone	Corticosteroid	289
Midazolam	Benzodiazepine	60
Morphine	Opioid agonist	67
Morphine sulfate	Opioid agonist	77
Mycophenolate mofetil	Antimetabolite immunosuppressant	383
Mycophenolic acid	Antimetabolite immunosuppressant	81
Nexium	Proton pump inhibitor	92
Nivolumab	Programmed death Receptor-1 blocking antibody	165
Ocrevus	CD20-directed cytolytic antibody	50
Ofev	Kinase inhibitor	109
Olanzapine	Atypical antipsychotic	97
Omeprazole	Proton pump inhibitor	107
Opdivo	Programmed death Receptor-1 blocking antibody	81
Opsumit	Endothelin receptor antagonist	397
Orenitram	Prostacycline vasodilator	73
Oxaliplatin	Platinum-based drug	144
Oxycodone hydrochloride	Opioid agonist	73
OxyContin	Opioid agonist	75
Paclitaxel	Microtubule inhibitor	157
Pantoprazole	Proton pump inhibitor	65
Pantoprazole sodium	Proton pump inhibitor	73
Pembrolizumab	Programmed death Receptor-1 blocking antibody	79
Pirfenidone	Pyridone	52
Plavix	P2Y12 platelet inhibitor	61
Pomalyst	Thalidomide analog	82
Pradaxa	Direct thrombin inhibitor	192
Prednisolone	Corticosteroid	227
Prednisone	Corticosteroid	762
Prevacid	Proton pump inhibitor	82
Prilosec	Proton pump inhibitor	76
Propofol	General anesthetic	82
Quetiapine	Atypical antipsychotic	53
Ramipril	Angiotensin converting enzyme inhibitor	55
Remdesivir	SARS-CoV-2 nucleotide analog RNA polymerase inhibitor	106
Remicade	Tumor necrosis factor blocker	70
Remodulin	Prostacycline vasodilator	276
Revlimid	Thalidomide analog	246
Rinvoq	Janus kinase inhibitor	67
Risperidone	Atypical antipsychotic	69
Rituximab	CD20-directed cytolytic antibody	376
Tacrolimus	Calcineurin inhibitor immunosuppressant	442
Tiotropium bromide	Anticholinergic	99
Tocilizumab	Interleukin-6 receptor antagonist	91
Tracleer	Endothelin receptor antagonist	206
Tramadol		79
Tysabri	Integrin receptor antagonist	86
Tyvaso	Prostacycline vasodilator	133
Uptravi	Prostacyclin receptor agonist	110
Vancomycin	Glycopeptide antibacterial	100
Velcade	Proteasome inhibitor	89
Veletri	Prostacycline vasodilator	80
Venetoclax	BCL-2 inhibitor	72
Vincristine		159
Vincristine sulfate	Vinca alkaloid	93
Vioxx		69
Xarelto	Factor Xa inhibitor	357

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 54 pharmacologic classes with 100 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Acute respiratory failure name, in order of name
Class	Reports with this term
Alkylating drug	617
Angiotensin 2 receptor blocker	123
Angiotensin converting enzyme inhibitor	181
Anthracycline topoisomerase inhibitor	290
Anti-epileptic agent	238
Anticholinergic	149
Antimetabolite immunosuppressant	519
Atypical antipsychotic	541
Azole antifungal	104
BCL-2 inhibitor	109
Benzodiazepine	399
beta-Adrenergic blocker	195
Biguanide	219
Bisphosphonate	103
Calcineurin inhibitor immunosuppressant	674
Calcium channel blocker	152
CD20-directed cytolytic antibody	495
CD38-directed cytolytic antibody	110
Cephalosporin antibacterial	151
Corticosteroid	2,002
Direct thrombin inhibitor	193
Endothelin receptor antagonist	1,135
Factor Xa inhibitor	557
Folate analog metabolic inhibitor	513
General anesthetic	109
Glycopeptide antibacterial	120
Integrin receptor antagonist	103
Interleukin-6 receptor antagonist	145
Janus kinase inhibitor	266
Kinase inhibitor	869
Loop diuretic	184
Macrolide antimicrobial	117
Microtubule inhibitor	235
Nonsteroidal anti-inflammatory drug	357
Nucleoside metabolic inhibitor	642
Opioid agonist	689
P2Y12 platelet inhibitor	176
Penem antibacterial	101
Penicillin-class antibacterial	104
Phosphodiesterase 5 inhibitor	167
Platinum-based drug	568
Programmed death Receptor-1 blocking antibody	524
Prostacyclin receptor agonist	118
Prostacycline vasodilator	649
Proteasome inhibitor	263
Proton pump inhibitor	771
Pyridone	128
SARS-CoV-2 nucleotide analog RNA polymerase inhibitor	121
Serotonin reuptake inhibitor	131
Soluble guanylate cyclase stimulator	121
Thalidomide analog	486
Topoisomerase inhibitor	230
Tumor necrosis factor blocker	291
Vascular endothelial growth factor inhibitor	131

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Acute respiratory failure, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Acute respiratory failure
Age	Reports	Share
Under 2	270	1.4%
2 to 11	295	1.6%
12 to 17	244	1.3%
18 to 44	2,269	12%
45 to 64	4,965	26.3%
65 to 74	3,779	20%
75 and over	3,394	18%
Age not given	3,649	19.3%

Sex of the patient in the reports that record Acute respiratory failure
Sex	Reports	Share
Female	8,690	46.1%
Male	8,700	46.1%
Unknown or not given	1,475	7.8%

Age and sex are as the report gives them. 61.6% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Acute respiratory failure: adverse event reports that record this term. https://reportedreactions.com/reaction/acute-respiratory-failure/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 1 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 1 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Oct 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Acute respiratory failure mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

To the top of the page