Activities of daily living impaired adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to March 2017, FDA received 19,783 adverse event reports that record the MedDRA preferred term Activities of daily living impaired. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 0 reports in the 12 months to June 2026 and 0 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Reports for female patients were 67% of the reports that record this term and 52.7% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 142 drug pages with 25 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Activities of daily living impaired name as a suspect product, in order of name
Drug	Class	Reports with this term
Abilify	Atypical antipsychotic	56
Actemra	Interleukin-6 receptor antagonist	58
Actonel	Bisphosphonate	50
Alprazolam	Benzodiazepine	45
Ambrisentan	Endothelin receptor antagonist	25
Ampyra	Potassium channel blocker	903
Androgel		32
Arava	Antirheumatic agent	39
Arimidex	Aromatase inhibitor	42
Aspirin	Nonsteroidal anti-inflammatory drug	35
Atenolol	beta-Adrenergic blocker	26
Atorvastatin		47
Aubagio	Pyrimidine synthesis inhibitor	66
Avandia		72
Avelox		33
Baclofen	gamma-Aminobutyric acid-ergic agonist	47
Bextra		46
Boniva		53
Botox	Acetylcholine release inhibitor	39
Brilinta	P2Y12 platelet inhibitor	35
Bupivacaine hcl	Amide local anesthetic	77
Bupropion hydrochloride	Aminoketone	48
Butrans	Partial opioid agonist	25
Celebrex	Nonsteroidal anti-inflammatory drug	198
Champix		59
Chantix	Partial cholinergic nicotinic agonist	464
Cimzia	Tumor necrosis factor blocker	25
Cipro	Corticosteroid	60
Ciprofloxacin	Fluoroquinolone antibacterial	87
Cisplatin	Platinum-based drug	29
Citalopram	Serotonin reuptake inhibitor	42
Citalopram hydrobromide	Serotonin reuptake inhibitor	35
Clonazepam	Benzodiazepine	27
Copaxone		34
Crestor	HMG-CoA reductase inhibitor	174
Cymbalta		270
Depakote	Anti-epileptic agent	192
Depo-Testosterone	Androgen	57
Desvenlafaxine succinate	Serotonin and norepinephrine reuptake inhibitor	103
Dexamethasone	Corticosteroid	38
Digoxin	Cardiac glycoside	117
Dilantin	Anti-epileptic agent	55
Duodopa		29
Effexor	Serotonin and norepinephrine reuptake inhibitor	189
Enbrel	Tumor necrosis factor blocker	738
Evista	Estrogen Agonist/Antagonist	26
Exelon	Cholinesterase inhibitor	29
Fentanyl Transdermal System		26
Fluoxetine	Serotonin reuptake inhibitor	33
Forteo	Parathyroid hormone analog	125
Fosamax	Bisphosphonate	79
Gabapentin	Anti-epileptic agent	167
Geodon	Atypical antipsychotic	82
Humira		699
Humira 40 Mg/0 8 Ml Pen		25
Ibuprofen	Nonsteroidal anti-inflammatory drug	36
Keppra		31
Lamictal	Anti-epileptic agent	53
Lamotrigine	Anti-epileptic agent	46
Lasix	Loop diuretic	28
Leflunomide	Antirheumatic agent	28
Letairis	Endothelin receptor antagonist	33
Levaquin		193
Levofloxacin	Fluoroquinolone antibacterial	68
Lexapro	Serotonin reuptake inhibitor	43
Lipitor	HMG-CoA reductase inhibitor	263
Lisinopril	Angiotensin converting enzyme inhibitor	65
Lupron Depot		56
Lyrica		1,050
Methotrexate	Folate analog metabolic inhibitor	127
Methotrexate sodium	Folate analog metabolic inhibitor	60
Metoclopramide	Dopamine-2 receptor antagonist	2,731
Metoclopramide hydrochloride	Dopamine-2 receptor antagonist	88
Metoprolol	beta-Adrenergic blocker	31
Mirapex		25
Mirena	Progestin	147
Mirtazapine		36
Morphine	Opioid agonist	27
Morphine sulfate	Opioid agonist	49
Neulasta	Leukocyte growth factor	25
Neurontin		196
Nexavar	Kinase inhibitor	35
Nexium	Proton pump inhibitor	186
Norvasc	Calcium channel blocker	28
Olanzapine	Atypical antipsychotic	29
Omeprazole	Proton pump inhibitor	43
OxyContin	Opioid agonist	155
Paxil	Serotonin reuptake inhibitor	67
Pegasys	Interferon alpha	44
Plaquenil	Antimalarial	50
Plavix	P2Y12 platelet inhibitor	28
Pradaxa	Direct thrombin inhibitor	30
Prednisone	Corticosteroid	123
Premarin	Estrogen	37
Prilosec	Proton pump inhibitor	41
Pristiq	Serotonin and norepinephrine reuptake inhibitor	43
Prolia	RANK ligand inhibitor	376
Prozac	Serotonin reuptake inhibitor	34
Rebif	Interferon beta	84
Reclast	Bisphosphonate	71
Reglan	Dopamine-2 receptor antagonist	93
Remicade	Tumor necrosis factor blocker	82
Revlimid	Thalidomide analog	54
Ribavirin	Nucleoside analog antiviral	60
Risperdal	Atypical antipsychotic	47
Risperidone	Atypical antipsychotic	43
Rituxan	CD20-directed cytolytic antibody	37
Seroquel	Atypical antipsychotic	393
Sertraline	Serotonin reuptake inhibitor	35
Simvastatin	HMG-CoA reductase inhibitor	231
Soliris	Complement inhibitor	72
Suboxone	Opioid antagonist	52
Sulfasalazine	Aminosalicylate	46
Sutent	Kinase inhibitor	54
Symbicort	Corticosteroid	86
Symbicort Pmdi		35
Synthroid	l-Thyroxine	36
Tecfidera		30
Tiotropium bromide	Anticholinergic	40
Topamax		39
Tramadol		26
Tylenol	Expectorant	25
Tysabri	Integrin receptor antagonist	44
Velcade	Proteasome inhibitor	25
Venlafaxine	Serotonin and norepinephrine reuptake inhibitor	33
Venlafaxine hcl	Serotonin and norepinephrine reuptake inhibitor	26
Venlafaxine hydrochloride	Serotonin and norepinephrine reuptake inhibitor	94
Vioxx		70
Vivitrol		26
Xanax	Benzodiazepine	97
Xarelto	Factor Xa inhibitor	36
Xeljanz	Janus kinase inhibitor	163
Xenazine	Vesicular monoamine transporter 2 inhibitor	28
Xtandi	Androgen receptor inhibitor	45
Xyrem	Central nervous system depressant	274
Yasmin		36
Yaz		55
Zocor	HMG-CoA reductase inhibitor	31
Zoloft	Serotonin reuptake inhibitor	144
Zometa		40
Zyprexa	Atypical antipsychotic	54
Zyrtec	Histamine-1 receptor antagonist	35

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 56 pharmacologic classes with 50 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Activities of daily living impaired name, in order of name
Class	Reports with this term
Acetylcholine release inhibitor	51
Amide local anesthetic	93
Aminoketone	94
Aminosalicylate	51
Androgen	77
Angiotensin 2 receptor blocker	65
Angiotensin converting enzyme inhibitor	81
Anti-epileptic agent	554
Anticholinergic	65
Antimalarial	76
Antirheumatic agent	67
Aromatase inhibitor	84
Atypical antipsychotic	868
Benzodiazepine	255
beta-Adrenergic blocker	140
Bisphosphonate	231
Calcium channel blocker	60
Cardiac glycoside	117
CD20-directed cytolytic antibody	59
Central nervous system depressant	274
Central nervous system stimulant	93
Complement inhibitor	72
Corticosteroid	443
Dopamine-2 receptor antagonist	2,912
Endothelin receptor antagonist	91
Estrogen	71
Fluoroquinolone antibacterial	176
Folate analog metabolic inhibitor	189
gamma-Aminobutyric acid-ergic agonist	75
Histamine-1 receptor antagonist	50
HMG-CoA reductase inhibitor	741
Interferon beta	107
Interleukin-6 receptor antagonist	58
Janus kinase inhibitor	172
Kinase inhibitor	190
l-Thyroxine	73
Mood stabilizer	69
Nonsteroidal anti-inflammatory drug	370
Nucleoside analog antiviral	62
Nucleoside metabolic inhibitor	60
Opioid agonist	441
Opioid antagonist	58
P2Y12 platelet inhibitor	76
Parathyroid hormone analog	125
Partial cholinergic nicotinic agonist	471
Platinum-based drug	59
Potassium channel blocker	903
Progestin	181
Prostacycline vasodilator	56
Proton pump inhibitor	330
Pyrimidine synthesis inhibitor	66
RANK ligand inhibitor	386
Serotonin and norepinephrine reuptake inhibitor	512
Serotonin reuptake inhibitor	535
Thalidomide analog	63
Tumor necrosis factor blocker	883

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Activities of daily living impaired, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Activities of daily living impaired
Age	Reports	Share
Under 2	13	0.1%
2 to 11	74	0.4%
12 to 17	153	0.8%
18 to 44	2,414	12.2%
45 to 64	4,433	22.4%
65 to 74	1,804	9.1%
75 and over	1,431	7.2%
Age not given	9,461	47.8%

Sex of the patient in the reports that record Activities of daily living impaired
Sex	Reports	Share
Female	13,257	67%
Male	5,640	28.5%
Unknown or not given	886	4.5%

Age and sex are as the report gives them. 81.5% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Activities of daily living impaired: adverse event reports that record this term. https://reportedreactions.com/reaction/activities-of-daily-living-impaired/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 29 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Activities of daily living impaired mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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