Spinal osteoarthritis adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 8,657 adverse event reports that record the MedDRA preferred term Spinal osteoarthritis. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 380 reports in the 12 months to June 2026 and 401 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 1 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 119 drug pages with 25 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Spinal osteoarthritis name as a suspect product, in order of name
Drug	Class	Reports with this term
Abatacept	Selective T cell costimulation modulator	33
Actemra	Interleukin-6 receptor antagonist	79
Actonel	Bisphosphonate	91
Advair Hfa	Corticosteroid	46
Albuterol sulfate	beta2-Adrenergic agonist	31
Alendronate sodium	Bisphosphonate	528
Amlodipine	Calcium channel blocker	45
Amphotericin b	Lipid-based polyene antifungal	25
Aranesp	Erythropoiesis-stimulating agent	26
Arava	Antirheumatic agent	28
Aredia		338
Aspirin	Nonsteroidal anti-inflammatory drug	25
Atripla		92
Avonex	Interferon beta	131
Bisoprolol	beta-Adrenergic blocker	30
Boniva		126
Byetta	GLP-1 receptor agonist	25
Calcium Carbonate Cholecalciferol		27
Candesartan	Angiotensin 2 receptor blocker	30
Candesartan cilexetil	Angiotensin 2 receptor blocker	39
Carboplatin	Platinum-based drug	36
Carvedilol	alpha-Adrenergic blocker	40
Celebrex	Nonsteroidal anti-inflammatory drug	51
Celecoxib	Nonsteroidal anti-inflammatory drug	26
Certolizumab pegol	Tumor necrosis factor blocker	36
Cholecalciferol		34
Cimzia	Tumor necrosis factor blocker	52
Clopidogrel	P2Y12 platelet inhibitor	28
Complera	Human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor	45
Cosentyx	Interleukin-17A antagonist	133
Cotrimoxazole		25
Crestor	HMG-CoA reductase inhibitor	34
Cyclophosphamide	Alkylating drug	27
Dexamethasone	Corticosteroid	44
Diclofenac	Nonsteroidal anti-inflammatory drug	29
Digitoxin		30
Digoxin	Cardiac glycoside	85
Enbrel	Tumor necrosis factor blocker	313
Erelzi		58
Esomeprazole	Proton pump inhibitor	31
Estraderm		28
Etanercept	Tumor necrosis factor blocker	42
Ezetimibe	Dietary cholesterol absorption inhibitor	36
Folic acid		32
Forteo	Parathyroid hormone analog	66
Fosamax	Bisphosphonate	1,205
Fosamax Plus D		273
Furosemide	Loop diuretic	38
Gabapentin	Anti-epileptic agent	43
Gilenya	Sphingosine 1-phosphate receptor modulator	75
Humira		918
Hydrochlorothiazide	Thiazide diuretic	34
Hydroxychloroquine	Antimalarial	27
Hygroton		25
Ibuprofen	Nonsteroidal anti-inflammatory drug	58
Imbruvica	Kinase inhibitor	25
Indapamide	Thiazide-like diuretic	29
Infliximab	Tumor necrosis factor blocker	57
Janumet	Biguanide	50
Januvia	Dipeptidyl peptidase 4 inhibitor	121
Keytruda	Programmed death Receptor-1 blocking antibody	35
Leflunomide	Antirheumatic agent	67
Lipitor	HMG-CoA reductase inhibitor	38
Lisinopril	Angiotensin converting enzyme inhibitor	26
Lyrica		115
Marcumar		27
Methotrexate	Folate analog metabolic inhibitor	298
Methotrexate sodium	Folate analog metabolic inhibitor	57
Metoclopramide	Dopamine-2 receptor antagonist	35
Metoprolol	beta-Adrenergic blocker	25
Morphine sulfate	Opioid agonist	44
Myfortic	Antimetabolite immunosuppressant	25
Nebivolol	beta-Adrenergic blocker	27
Nexium	Proton pump inhibitor	170
Nitrendipine		32
Ocrevus	CD20-directed cytolytic antibody	50
Omeprazole	Proton pump inhibitor	57
Orencia	Selective T cell costimulation modulator	43
Otezla	Phosphodiesterase 4 inhibitor	30
Oxycodone hydrochloride	Opioid agonist	54
OxyContin	Opioid agonist	48
Pantoprazole	Proton pump inhibitor	38
Prednisolone	Corticosteroid	29
Prednisone	Corticosteroid	140
Pregabalin		29
Premarin	Estrogen	32
Prilosec	Proton pump inhibitor	46
Prograf	Calcineurin inhibitor immunosuppressant	35
Prolia	RANK ligand inhibitor	123
Provera	Progestin	29
Rebif	Interferon beta	29
Remicade	Tumor necrosis factor blocker	92
Revlimid	Thalidomide analog	32
Rinvoq	Janus kinase inhibitor	118
Rituxan	CD20-directed cytolytic antibody	27
Rituximab	CD20-directed cytolytic antibody	92
Rosuvastatin	HMG-CoA reductase inhibitor	32
Sandostatin LAR Depot		33
Seroquel	Atypical antipsychotic	54
Simponi	Tumor necrosis factor blocker	42
Simvastatin	HMG-CoA reductase inhibitor	30
Skyrizi	Interleukin-23 antagonist	55
Sodium bicarbonate	Osmotic laxative	32
Stribild	Cytochrome P450 3A inhibitor	57
Sulfasalazine	Aminosalicylate	50
Tacrolimus	Calcineurin inhibitor immunosuppressant	41
Tamsulosin hydrochloride	alpha-Adrenergic blocker	28
Tecfidera		40
Tiotropium bromide	Anticholinergic	28
Torsemide	Loop diuretic	32
Tramadol		35
Truvada	Human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor	142
Tysabri	Integrin receptor antagonist	68
Valsartan	Angiotensin 2 receptor blocker	81
Vioxx		185
Viread	Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	70
Xeljanz	Janus kinase inhibitor	103
Xyrem	Central nervous system depressant	80
Zometa		507

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 45 pharmacologic classes with 50 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Spinal osteoarthritis name, in order of name
Class	Reports with this term
alpha-Adrenergic blocker	107
Aminosalicylate	63
Angiotensin 2 receptor blocker	210
Angiotensin converting enzyme inhibitor	78
Anti-epileptic agent	74
Antimalarial	58
Antirheumatic agent	95
Aromatase inhibitor	54
Atypical antipsychotic	99
beta-Adrenergic blocker	120
beta2-Adrenergic agonist	64
Biguanide	63
Bisphosphonate	1,863
Calcineurin inhibitor immunosuppressant	84
Calcium channel blocker	69
Cardiac glycoside	85
CD20-directed cytolytic antibody	205
Central nervous system depressant	97
Corticosteroid	349
Cytochrome P450 3A inhibitor	61
Dipeptidyl peptidase 4 inhibitor	121
Estrogen	88
Folate analog metabolic inhibitor	367
GLP-1 receptor agonist	54
Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	72
HMG-CoA reductase inhibitor	191
Human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor	191
Integrin receptor antagonist	91
Interferon beta	166
Interleukin-17A antagonist	139
Interleukin-23 antagonist	57
Interleukin-6 receptor antagonist	104
Janus kinase inhibitor	248
Kinase inhibitor	200
Loop diuretic	72
Nonsteroidal anti-inflammatory drug	249
Opioid agonist	340
Parathyroid hormone analog	68
Platinum-based drug	60
Programmed death Receptor-1 blocking antibody	91
Proton pump inhibitor	418
RANK ligand inhibitor	131
Selective T cell costimulation modulator	76
Sphingosine 1-phosphate receptor modulator	75
Tumor necrosis factor blocker	685

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Spinal osteoarthritis, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Spinal osteoarthritis
Age	Reports	Share
Under 2	1	under 0.1%
2 to 11	2	under 0.1%
12 to 17	12	0.1%
18 to 44	532	6.1%
45 to 64	2,502	28.9%
65 to 74	1,369	15.8%
75 and over	746	8.6%
Age not given	3,493	40.3%

Sex of the patient in the reports that record Spinal osteoarthritis
Sex	Reports	Share
Female	5,578	64.4%
Male	2,594	30%
Unknown or not given	485	5.6%

Age and sex are as the report gives them. 65.6% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Spinal osteoarthritis: adverse event reports that record this term. https://reportedreactions.com/reaction/spinal-osteoarthritis/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 1 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 1 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Oct 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Spinal osteoarthritis mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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