Blood calcium increased adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 8,629 adverse event reports that record the MedDRA preferred term Blood calcium increased. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 514 reports in the 12 months to June 2026 and 394 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 1 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 105 drug pages with 50 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Blood calcium increased name as a suspect product, in order of name
Drug	Class	Reports with this term
Acetaminophen		200
Albuterol	beta2-Adrenergic agonist	134
Albuterol sulfate	beta2-Adrenergic agonist	136
Allopurinol	Xanthine oxidase inhibitor	84
Amiodarone hydrochloride	Antiarrhythmic	55
Amlodipine besylate	Dihydropyridine calcium channel blocker	55
Aranesp	Erythropoiesis-stimulating agent	86
Azithromycin	Macrolide antimicrobial	68
Betamethasone		51
Biotin	Arteriolar vasodilator	56
Bisacodyl		99
Budesonide	Corticosteroid	142
Budesonide Formoterol Fumarate		58
Calcitriol	Vitamin D3 analog	89
Calcium		95
Calcium carbonate	Blood coagulation factor	91
Candesartan	Angiotensin 2 receptor blocker	110
Ceftriaxone sodium	Cephalosporin antibacterial	64
Crestor	HMG-CoA reductase inhibitor	75
Dexamethasone	Corticosteroid	62
Dexilant	Proton pump inhibitor	153
Dexlansoprazole	Proton pump inhibitor	50
Dextrose		72
Dipyrone		65
Distigmine Bromide		52
Docusate sodium		53
Domperidone		88
Dulcolax	Osmotic laxative	50
Enbrel	Tumor necrosis factor blocker	81
Formoterol fumarate	beta2-Adrenergic agonist	58
Forteo	Parathyroid hormone analog	1,918
Fosamax	Bisphosphonate	66
Fragmin	Anti-coagulant	68
Furazolidone		64
Gabapentin	Anti-epileptic agent	74
Heparin sodium	Anti-coagulant	61
Herbals		60
Humira		182
Hydromorphone		52
Hydromorphone hydrochloride	Opioid agonist	72
Ibrance	Kinase inhibitor	76
Imbruvica	Kinase inhibitor	67
Influenza virus vaccine		70
Insulin aspart	Insulin analog	54
Ipratropium		66
Ipratropium bromide	Anticholinergic	183
Jublia	Azole antifungal	108
Lansoprazole	Proton pump inhibitor	154
Lanthanum carbonate	Phosphate binder	64
Levothyroxine sodium	l-Thyroxine	106
Lipitor	HMG-CoA reductase inhibitor	69
Magnesium oxide	Calculi dissolution agent	56
Melatonin		53
Metronidazole	Nitroimidazole antimicrobial	82
Montelukast	Leukotriene receptor antagonist	73
Morphine Hydrochloride		65
Morphine sulfate	Opioid agonist	114
Nasonex	Corticosteroid	88
Natpara		142
Nitroglycerin	Nitrate vasodilator	147
Norepinephrine bitartrate	Catecholamine	61
Nucala	Interleukin-5 antagonist	95
Omalizumab	Anti-IgE	83
Ondansetron	Serotonin-3 receptor antagonist	73
Otrivin		64
Pantoprazole	Proton pump inhibitor	64
Pantoprazole sodium	Proton pump inhibitor	111
Parathyroid Hormone		68
Phytonadione		78
Polyethylene glycol 3350	Osmotic laxative	56
Pomalyst	Thalidomide analog	124
Potassium chloride	Osmotic laxative	61
Pramipexole	Nonergot dopamine agonist	75
Pregabalin		104
Prevacid	Proton pump inhibitor	88
Prevnar 13		83
Prolia	RANK ligand inhibitor	322
Quetiapine fumarate	Atypical antipsychotic	71
Ranitidine	Histamine-2 receptor antagonist	65
Ranitidine hydrochloride	Histamine-2 receptor antagonist	50
Revlimid	Thalidomide analog	302
Risedronate sodium	Bisphosphonate	91
Rosuvastatin	HMG-CoA reductase inhibitor	74
Rosuvastatin calcium	HMG-CoA reductase inhibitor	75
Sennosides		89
Senokot		90
Sensipar	Calcium-sensing receptor agonist	229
Simvastatin	HMG-CoA reductase inhibitor	58
Singulair	Leukotriene receptor antagonist	85
Sodium phosphate monobasic		53
Synthroid	l-Thyroxine	100
Teriparatide	Parathyroid hormone analog	85
Tiotropium bromide	Anticholinergic	77
Tiotropium bromide monohydrate		50
Trazodone		62
Trelegy Ellipta	Anticholinergic	56
Tymlos		360
Vasopressin		58
Vitamin d	Provitamin D2 compound	91
Vitamin K1		59
Xgeva	RANK ligand inhibitor	61
Xolair	Anti-IgE	67
Zocor	HMG-CoA reductase inhibitor	66
Zometa		79
Zopiclone		100

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 56 pharmacologic classes with 50 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Blood calcium increased name, in order of name
Class	Reports with this term
Angiotensin 2 receptor blocker	219
Angiotensin converting enzyme inhibitor	72
Anti-coagulant	229
Anti-epileptic agent	78
Anti-IgE	150
Antiarrhythmic	55
Anticholinergic	318
Aromatase inhibitor	69
Arteriolar vasodilator	56
Atypical antipsychotic	169
Azole antifungal	108
BCL-2 inhibitor	52
beta-Adrenergic agonist	77
beta2-Adrenergic agonist	349
Bisphosphonate	246
Blood coagulation factor	167
Calcium channel blocker	68
Calcium-sensing receptor agonist	312
Calculi dissolution agent	67
Catecholamine	95
Cephalosporin antibacterial	106
Corticosteroid	717
Dihydropyridine calcium channel blocker	61
Erythropoiesis-stimulating agent	111
Folate analog metabolic inhibitor	61
GLP-1 receptor agonist	110
Histamine-2 receptor antagonist	118
HMG-CoA reductase inhibitor	430
Insulin analog	175
Interleukin-5 antagonist	133
Janus kinase inhibitor	83
Kinase inhibitor	480
l-Thyroxine	209
Leukotriene receptor antagonist	201
Macrolide antimicrobial	77
Neuraminidase inhibitor	88
Nitrate vasodilator	147
Nitroimidazole antimicrobial	82
Nonergot dopamine agonist	112
Opioid agonist	218
Osmotic laxative	321
Parathyroid hormone analog	2,003
Phosphate binder	111
Programmed death Receptor-1 blocking antibody	58
Proteasome inhibitor	107
Proton pump inhibitor	641
Provitamin D2 compound	137
RANK ligand inhibitor	420
Serotonin reuptake inhibitor	54
Serotonin-3 receptor antagonist	97
Thalidomide analog	452
Tumor necrosis factor blocker	111
Vitamin C	103
Vitamin D3 analog	89
Vitamin K antagonist	58
Xanthine oxidase inhibitor	84

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Blood calcium increased, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Blood calcium increased
Age	Reports	Share
Under 2	37	0.4%
2 to 11	59	0.7%
12 to 17	42	0.5%
18 to 44	434	5%
45 to 64	1,719	19.9%
65 to 74	1,438	16.7%
75 and over	1,520	17.6%
Age not given	3,380	39.2%

Sex of the patient in the reports that record Blood calcium increased
Sex	Reports	Share
Female	6,076	70.4%
Male	1,987	23%
Unknown or not given	566	6.6%

Age and sex are as the report gives them. 74.2% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Blood calcium increased: adverse event reports that record this term. https://reportedreactions.com/reaction/blood-calcium-increased/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 1 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 1 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Oct 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Blood calcium increased mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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