MedDRA preferred term

Platelet count abnormal: adverse event reports recording this term

5,939 reports to FDA record it, 2004–2026; 0% of the database.

Read first · FDA's statement on these data

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product. openFDA, FDA

FDA adds: "There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event." The information in these reports "cannot be used to estimate the incidence of these events."

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

5,939
reports recording the term: 0% of all reports; 401
reports, 12 months to June 2026: 377 in the 12 months before; 67.7%
marked serious by the reporter: 57.4% across all reports; 6%
record death among outcomes, as reported: 9.1% across all reports

5,939 reports in FDA's adverse event database record the MedDRA term "Platelet count abnormal": 0% of all reports received between January 2004 and June 2026. Coders pick the term that best matches the reporter's description.

401 reports recorded it in the 12 months to June 2026, close to the 377 of the 12 months before. FDA releases FAERS data quarterly, so the newest months are incomplete and grow in later releases. Of reports recording this term, 67.7% are marked serious, 6% include death among the outcomes and 29.1% include hospitalisation, as reported.

The drugs listed most often as suspect products in those reports are Nplate, Jakafi and Soliris. That order mostly follows how many reports each drug has overall; the table also gives the term's share within each drug's own reports. FDA states that "a causal relationship cannot be established between product and reactions listed in a report" and that for any given report "there is no certainty that a suspected drug caused the event."

Reports by month, five years

FDA releases FAERS data quarterly, so the newest months are incomplete and grow in later releases.

Drugs listed as suspect products in these reports

Drug	Class	Reports with this term	Share of the drug's own reports
Nplate	Thrombopoietin receptor agonist	905	7.8%
Jakafi	Janus kinase inhibitor	687	1.2%
Soliris	Complement inhibitor	275	0.5%
Revlimid	Thalidomide analog	204	0.1%
Promacta	Thrombopoietin receptor agonist	200	1.4%
Rituximab	CD20-directed cytolytic antibody	178	0.1%
Imbruvica	Kinase inhibitor	175	0.3%
Eltrombopag olamine	Thrombopoietin receptor agonist	172	5.6%
Venclexta	BCL-2 inhibitor	166	0.5%
Dexamethasone	Corticosteroid	120	0.1%
Doptelet	—	101	5.2%
Ruxolitinib	Janus kinase inhibitor	90	1%
Prednisone	Corticosteroid	87	0%
Cyclophosphamide	Alkylating drug	86	0.1%
Carboplatin	Platinum-based drug	84	0.1%
Cytarabine	Nucleoside metabolic inhibitor	78	0.2%
Methotrexate	Folate analog metabolic inhibitor	73	0%
Eltrombopag	Thrombopoietin receptor agonist	71	2.6%
Zejula	Poly(ADP-Ribose) polymerase inhibitor	69	0.4%
Enbrel	Tumor necrosis factor blocker	61	0%
Ayvakit	Kinase inhibitor	57	0.5%
Cisplatin	Platinum-based drug	56	0.1%
Oxaliplatin	Platinum-based drug	54	0.1%
Kisqali	Kinase inhibitor	53	0.2%
Revolade	—	53	1.5%

Drugs with a page on this site, ordered by the number of their reports recording this term. The last column is the term's share within that drug's own reports, against 0% across the whole database. FDA states that adverse event reports "represent a small percentage of total usage numbers of a product", that "common products may have a higher number of adverse events due to the higher total number of people using the product", and that the data "by themselves are not an indicator of the safety profile of the drug or biologic."

By pharmacologic class

Class	Reports with this term	Share of class reports	Median drug in class
Thrombopoietin receptor agonist	1,372	4%	2.6%
Janus kinase inhibitor	789	0.2%	0%
Kinase inhibitor	644	0.1%	0%
Corticosteroid	286	0%	0%
Complement inhibitor	285	0.4%	0.1%
Thalidomide analog	271	0.1%	0.1%
Nucleoside metabolic inhibitor	217	0.1%	0%
BCL-2 inhibitor	207	0.4%	0.4%
CD20-directed cytolytic antibody	197	0.1%	0%
Platinum-based drug	194	0.1%	0.1%

Classes ordered by count. Class shares follow the class's overall report volume as much as anything else.

Patients in these reports

Patient age

Under 20.5%32

2 to 111%61

12 to 170.8%47

18 to 448%476

45 to 6417.9%1,066

65 to 7414.1%836

75 and over9.9%588

Age not given47.7%2,833

Patient sex

Female43.3%2,572

Male34.9%2,074

Not given21.8%1,293

Grey bar: all 20,646,523 reports in the database. 65.6% of these reports give the United States as the country.

Questions about "Platelet count abnormal"

What does "Platelet count abnormal" mean in an adverse event report?

It is a MedDRA preferred term, the dictionary FDA uses to code what a reporter described. The report's own description is not published by openFDA and is not shown here.

How many reports record platelet count abnormal?

5,939 reports through June 2026 (0% of all reports), 401 of them in the latest 12 months.

Which drugs appear most often in these reports?

Nplate (905), Jakafi (687), Soliris (275), Revlimid (204) and Promacta (200). Drugs with many reports overall lead almost every term's list. FDA states that adverse event reports "represent a small percentage of total usage numbers of a product", that "common products may have a higher number of adverse events due to the higher total number of people using the product", and that the data "by themselves are not an indicator of the safety profile of the drug or biologic."

Does a drug appearing here mean it was responsible for this reaction?

No. FDA states that "a causal relationship cannot be established between product and reactions listed in a report" and that for any given report "there is no certainty that a suspected drug caused the event."

I have this symptom. What should I do?

This site cannot assess anyone. A pharmacist or clinician can; for an emergency, call the local emergency number. Nothing on this page is medical advice.

Where this comes from. Counts are built from the openFDA Drug Adverse Event (FAERS) bulk export released 28 Sep 2026, which holds reports FDA received through 30 Jun 2026. Drug names are as reported, resolved to the brand or generic name on the FDA label where openFDA's harmonisation matched them; classes are the pharmacologic class (EPC) from the label and the National Drug Code Directory of 17 Sep 2026. Terms are pooled across spelling and capitalisation variants of one MedDRA preferred term. No report narrative, lot number, patient detail or reporter identity is published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.

Drug data (FAERS) through 30 Jun 2026; device data (MAUDE) through 31 Aug 2026. Not medical advice.