Reported Reactions

Adverse event reports that FDA received

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Musculoskeletal chest pain adverse event reports that record this term

Kind of term
MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.

Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on . The data have the reports that FDA received through .

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.

Source: openFDA, Drug Adverse Event Overview. The site read the page on .

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.

Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on .

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From February 2004 to June 2026, FDA received 15,264 adverse event reports that record the MedDRA preferred term Musculoskeletal chest pain. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 840 reports in the 12 months to June 2026 and 782 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

By reports in the 12 months to June 2026, this term was number 696 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 840 (0.1%) record this term. Reports for female patients were 62.8% of the reports that record this term and 52.7% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 101 drug pages with 50 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.

Source: openFDA, Drug Adverse Event Overview. The site read the page on .

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.

Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of . The site read the page on .

Drugs that the reports with the term Musculoskeletal chest pain name as a suspect product, in order of name
DrugClassReports with this term
Acetaminophen56
Aclasta59
ActemraInterleukin-6 receptor antagonist109
ActonelBisphosphonate64
AfinitorKinase inhibitor81
Albuterol sulfatebeta2-Adrenergic agonist89
Alendronate sodiumBisphosphonate79
AmbrisentanEndothelin receptor antagonist71
AmlodipineCalcium channel blocker80
AnastrozoleAromatase inhibitor55
Aredia100
AspirinNonsteroidal anti-inflammatory drug64
Atorvastatin116
AvastinVascular endothelial growth factor inhibitor99
AvonexInterferon beta50
BevacizumabVascular endothelial growth factor inhibitor54
Boniva153
CabometyxKinase inhibitor79
CapecitabineNucleoside metabolic inhibitor56
CarboplatinPlatinum-based drug63
CiprofloxacinFluoroquinolone antibacterial76
CosentyxInterleukin-17A antagonist245
CrestorHMG-CoA reductase inhibitor52
CyclophosphamideAlkylating drug58
DexamethasoneCorticosteroid199
DiclofenacNonsteroidal anti-inflammatory drug69
Diclofenac sodiumNonsteroidal anti-inflammatory drug70
DigoxinCardiac glycoside67
DocetaxelMicrotubule inhibitor54
DupixentInterleukin-4 receptor alpha antagonist140
EliquisFactor Xa inhibitor56
EnbrelTumor necrosis factor blocker517
EntrestoAngiotensin 2 receptor blocker68
FemaraAromatase inhibitor65
ForteoParathyroid hormone analog282
FosamaxBisphosphonate227
FulvestrantEstrogen receptor antagonist71
GabapentinAnti-epileptic agent63
GilenyaSphingosine 1-phosphate receptor modulator101
HerceptinHER2/neu receptor antagonist50
Humira648
IbranceKinase inhibitor231
IbuprofenNonsteroidal anti-inflammatory drug52
InflectraTumor necrosis factor blocker78
InfliximabTumor necrosis factor blocker77
JakafiJanus kinase inhibitor78
KisqaliKinase inhibitor186
LenalidomideThalidomide analog79
LetrozoleAromatase inhibitor98
LipitorHMG-CoA reductase inhibitor68
Lyrica93
MepolizumabInterleukin-5 antagonist80
MetforminBiguanide86
MethotrexateFolate analog metabolic inhibitor239
Methotrexate sodiumFolate analog metabolic inhibitor58
MorphineOpioid agonist50
MounjaroGLP-1 receptor agonist67
NeulastaLeukocyte growth factor57
NexiumProton pump inhibitor65
NinlaroProteasome inhibitor57
NuvaringEstrogen68
OfevKinase inhibitor98
OmalizumabAnti-IgE66
OmeprazoleProton pump inhibitor73
OpsumitEndothelin receptor antagonist52
OtezlaPhosphodiesterase 4 inhibitor53
PaclitaxelMicrotubule inhibitor72
PantoprazoleProton pump inhibitor52
PomalystThalidomide analog125
PrednisoneCorticosteroid191
Pregabalin62
ProliaRANK ligand inhibitor224
RamiprilAngiotensin converting enzyme inhibitor73
ReclastBisphosphonate115
RemicadeTumor necrosis factor blocker109
RemodulinProstacycline vasodilator70
RepathaPCSK9 inhibitor106
RevlimidThalidomide analog446
RinvoqJanus kinase inhibitor89
RituximabCD20-directed cytolytic antibody111
SandostatinSomatostatin analog111
Sandostatin LAR Depot120
SkyriziInterleukin-23 antagonist50
SutentKinase inhibitor62
SymbicortCorticosteroid82
Tecfidera59
Tiotropium bromideAnticholinergic101
TrastuzumabHER2/neu receptor antagonist50
Tymlos59
TysabriIntegrin receptor antagonist105
TyvasoProstacycline vasodilator67
VedolizumabIntegrin receptor antagonist78
VelcadeProteasome inhibitor59
Vioxx212
XareltoFactor Xa inhibitor82
XeljanzJanus kinase inhibitor169
XolairAnti-IgE108
XtandiAndrogen receptor inhibitor102
Yasmin50
Yaz68
Zometa244

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 44 pharmacologic classes with 100 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.

Source: openFDA, Drug Adverse Event Overview. The site read the page on .

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.

Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of . The site read the page on .

Pharmacologic classes of the drugs that the reports with the term Musculoskeletal chest pain name, in order of name
ClassReports with this term
Androgen receptor inhibitor129
Angiotensin 2 receptor blocker138
Angiotensin converting enzyme inhibitor107
Anti-IgE174
Anticholinergic176
Aromatase inhibitor266
Atypical antipsychotic159
beta2-Adrenergic agonist125
Biguanide120
Bisphosphonate556
CD20-directed cytolytic antibody229
Corticosteroid740
Endothelin receptor antagonist207
Estrogen receptor antagonist132
Factor Xa inhibitor161
Fluoroquinolone antibacterial118
Folate analog metabolic inhibitor324
GLP-1 receptor agonist216
HER2/neu receptor antagonist145
HMG-CoA reductase inhibitor205
Integrin receptor antagonist205
Interleukin-17A antagonist247
Interleukin-4 receptor alpha antagonist154
Interleukin-5 antagonist109
Interleukin-6 receptor antagonist122
Janus kinase inhibitor342
Kinase inhibitor1,258
Microtubule inhibitor137
Nonsteroidal anti-inflammatory drug411
Nucleoside metabolic inhibitor157
Opioid agonist280
Parathyroid hormone analog295
PCSK9 inhibitor124
Platinum-based drug129
Programmed death Receptor-1 blocking antibody147
Prostacycline vasodilator224
Proteasome inhibitor193
Proton pump inhibitor318
RANK ligand inhibitor285
Somatostatin analog143
Sphingosine 1-phosphate receptor modulator114
Thalidomide analog660
Tumor necrosis factor blocker961
Vascular endothelial growth factor inhibitor162

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Musculoskeletal chest pain, by month, five years to June 2026
010020020222023202420252026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Musculoskeletal chest pain
AgeReportsShareShare as a bar
Under 27under 0.1%
2 to 11510.3%
12 to 171190.8%
18 to 441,80811.8%
45 to 644,45829.2%
65 to 742,41315.8%
75 and over1,59410.4%
Age not given4,81431.5%
Sex of the patient in the reports that record Musculoskeletal chest pain
SexReportsShareShare as a bar
Female9,59362.8%
Male4,63530.4%
Unknown or not given1,0366.8%

Age and sex are as the report gives them. 65.5% of these reports give the United States as the country.

Terms near this one

Official pages

The site checked these addresses on . The links open in a new tab.

Cite this page

Reported Reactions. Musculoskeletal chest pain: adverse event reports that record this term. https://reportedreactions.com/reaction/musculoskeletal-chest-pain/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of . Reports received through .

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Musculoskeletal chest pain mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.

Source: openFDA, Drug Adverse Event Overview. The site read the page on .

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.

Source: openFDA, Drug Adverse Event Overview. The site read the page on .

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.

Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on .