Ligament sprain adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From June 2004 to June 2026, FDA received 9,732 adverse event reports that record the MedDRA preferred term Ligament sprain. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 549 reports in the 12 months to June 2026 and 593 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

By reports in the 12 months to June 2026, this term was number 938 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 549 (under 0.1%) record this term. Reports for female patients were 67.3% of the reports that record this term and 52.7% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 91 drug pages with 25 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Ligament sprain name as a suspect product, in order of name
Drug	Class	Reports with this term
Abatacept	Selective T cell costimulation modulator	42
Abilify	Atypical antipsychotic	32
Aclasta		44
Actemra	Interleukin-6 receptor antagonist	187
Actonel	Bisphosphonate	38
Advate		112
Albuterol sulfate	beta2-Adrenergic agonist	29
Alendronate sodium	Bisphosphonate	160
Alprolix		26
Altuviiio		34
Ambrisentan	Endothelin receptor antagonist	52
Amoxicillin	Penicillin-class antibacterial	34
Ampyra	Potassium channel blocker	83
Apixaban	Factor Xa inhibitor	33
Aredia		47
Atorvastatin		27
Aubagio	Pyrimidine synthesis inhibitor	27
Avonex	Interferon beta	133
BeneFIX		29
Boniva		44
Certolizumab pegol	Tumor necrosis factor blocker	26
Ciprofloxacin	Fluoroquinolone antibacterial	44
Cosentyx	Interleukin-17A antagonist	140
Covid-19 Vaccine		25
Crestor	HMG-CoA reductase inhibitor	36
Dexamethasone	Corticosteroid	27
Dianeal Low Calcium Peritoneal Dialysis Solution with Dextrose		41
Dupixent	Interleukin-4 receptor alpha antagonist	190
Eliquis	Factor Xa inhibitor	67
Eloctate		53
Enbrel	Tumor necrosis factor blocker	359
Entresto	Angiotensin 2 receptor blocker	82
Forteo	Parathyroid hormone analog	193
Fosamax	Bisphosphonate	346
Fosamax Plus D		82
Gabapentin	Anti-epileptic agent	44
Gilenya	Sphingosine 1-phosphate receptor modulator	128
Hemlibra		117
Humalog	Insulin analog	28
Human immunoglobulin g	Human immunoglobulin G	68
Human Immunoglobulin G Hyaluronidase Recombinant Human		25
Humira		786
Ibrance	Kinase inhibitor	36
Imbruvica	Kinase inhibitor	72
Inflectra	Tumor necrosis factor blocker	84
Infliximab	Tumor necrosis factor blocker	53
Influenza virus vaccine		27
Jakafi	Janus kinase inhibitor	45
Kisqali	Kinase inhibitor	36
Levaquin		36
Lipitor	HMG-CoA reductase inhibitor	59
Lyrica		129
Mepolizumab	Interleukin-5 antagonist	26
Metformin	Biguanide	43
Methotrexate	Folate analog metabolic inhibitor	140
Methotrexate sodium	Folate analog metabolic inhibitor	25
Nexium	Proton pump inhibitor	92
Nuvaring	Estrogen	92
Ocrevus	CD20-directed cytolytic antibody	98
Omalizumab	Anti-IgE	79
Omeprazole	Proton pump inhibitor	29
Opsumit	Endothelin receptor antagonist	35
Orencia	Selective T cell costimulation modulator	41
Otezla	Phosphodiesterase 4 inhibitor	31
Oxycodone hydrochloride	Opioid agonist	34
Prednisone	Corticosteroid	98
Pregabalin		39
Prolia	RANK ligand inhibitor	77
Propecia	5-alpha reductase inhibitor	40
Ramipril	Angiotensin converting enzyme inhibitor	47
Rebif	Interferon beta	38
Remicade	Tumor necrosis factor blocker	87
Repatha	PCSK9 inhibitor	26
Revlimid	Thalidomide analog	107
Rinvoq	Janus kinase inhibitor	112
Rituximab	CD20-directed cytolytic antibody	84
Sandostatin	Somatostatin analog	44
Sandostatin LAR Depot		58
Simponi	Tumor necrosis factor blocker	32
Skyrizi	Interleukin-23 antagonist	84
Soliris	Complement inhibitor	25
Strensiq		31
Tecfidera		103
Tiotropium bromide	Anticholinergic	30
Tysabri	Integrin receptor antagonist	191
Vedolizumab	Integrin receptor antagonist	57
Xarelto	Factor Xa inhibitor	35
Xeljanz	Janus kinase inhibitor	172
Xolair	Anti-IgE	176
Xyrem	Central nervous system depressant	159
Zometa		63

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 59 pharmacologic classes with 25 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Ligament sprain name, in order of name
Class	Reports with this term
5-alpha reductase inhibitor	65
Angiotensin 2 receptor blocker	129
Angiotensin converting enzyme inhibitor	68
Anti-epileptic agent	93
Anti-IgE	255
Anticholinergic	45
Aromatase inhibitor	32
Atypical antipsychotic	99
Benzodiazepine	44
beta-Adrenergic blocker	35
beta2-Adrenergic agonist	53
Biguanide	50
Bisphosphonate	569
CD20-directed cytolytic antibody	252
Central nervous system depressant	173
Complement inhibitor	37
Corticosteroid	293
Endothelin receptor antagonist	138
Estrogen	99
Factor Xa inhibitor	137
Fluoroquinolone antibacterial	57
Folate analog metabolic inhibitor	169
GLP-1 receptor agonist	69
Histamine-1 receptor antagonist	34
HMG-CoA reductase inhibitor	102
Human immunoglobulin G	86
Insulin analog	88
Integrin receptor antagonist	254
Interferon beta	180
Interleukin-17A antagonist	157
Interleukin-23 antagonist	86
Interleukin-4 receptor alpha antagonist	197
Interleukin-5 antagonist	30
Interleukin-6 receptor antagonist	216
Janus kinase inhibitor	329
Kinase inhibitor	268
Leukotriene receptor antagonist	46
Mood stabilizer	29
Nonsteroidal anti-inflammatory drug	124
Nucleoside metabolic inhibitor	25
Opioid agonist	206
Parathyroid hormone analog	193
PCSK9 inhibitor	28
Penicillin-class antibacterial	34
Phosphodiesterase 4 inhibitor	31
Phosphodiesterase 5 inhibitor	45
Potassium channel blocker	87
Prostacycline vasodilator	57
Proton pump inhibitor	184
Pyrimidine synthesis inhibitor	43
RANK ligand inhibitor	77
Selective T cell costimulation modulator	83
Serotonin and norepinephrine reuptake inhibitor	66
Serotonin reuptake inhibitor	42
Somatostatin analog	50
Sphingosine 1-phosphate receptor modulator	142
Thalidomide analog	122
Tricyclic antidepressant	25
Tumor necrosis factor blocker	678

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Ligament sprain, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Ligament sprain
Age	Reports	Share
Under 2	12	0.1%
2 to 11	118	1.2%
12 to 17	214	2.2%
18 to 44	1,396	14.3%
45 to 64	2,667	27.4%
65 to 74	1,340	13.8%
75 and over	775	8%
Age not given	3,210	33%

Sex of the patient in the reports that record Ligament sprain
Sex	Reports	Share
Female	6,550	67.3%
Male	2,560	26.3%
Unknown or not given	622	6.4%

Age and sex are as the report gives them. 70.8% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Ligament sprain: adverse event reports that record this term. https://reportedreactions.com/reaction/ligament-sprain/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 29 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Ligament sprain mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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