Troponin increased adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 7,426 adverse event reports that record the MedDRA preferred term Troponin increased. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 715 reports in the 12 months to June 2026 and 630 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

By reports in the 12 months to June 2026, this term was number 787 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 715 (0.1%) record this term. Reports for male patients were 49.3% of the reports that record this term and 34.6% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 110 drug pages with 50 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Troponin increased name as a suspect product, in order of name
Drug	Class	Reports with this term
Acetaminophen		157
Albuterol	beta2-Adrenergic agonist	67
Albuterol sulfate	beta2-Adrenergic agonist	69
Allopurinol	Xanthine oxidase inhibitor	130
Amiodarone		63
Amiodarone hydrochloride	Antiarrhythmic	104
Amisulpride	Dopamine-2 receptor antagonist	54
Amlodipine	Calcium channel blocker	96
Amlodipine besylate	Dihydropyridine calcium channel blocker	105
Aranesp	Erythropoiesis-stimulating agent	78
Aripiprazole	Atypical antipsychotic	61
Aspirin	Nonsteroidal anti-inflammatory drug	149
Atorvastatin		134
Betamethasone		51
Biotin	Arteriolar vasodilator	58
Bisacodyl		65
Breo Ellipta	Corticosteroid	62
Calcitriol	Vitamin D3 analog	75
Candesartan	Angiotensin 2 receptor blocker	69
Carboplatin	Platinum-based drug	156
Ceftriaxone	Cephalosporin antibacterial	72
Ceftriaxone sodium	Cephalosporin antibacterial	65
Cisplatin	Platinum-based drug	55
Clonazepam	Benzodiazepine	86
Clopidogrel	P2Y12 platelet inhibitor	50
Clozapine	Atypical antipsychotic	389
Clozaril	Atypical antipsychotic	629
Cyclophosphamide	Alkylating drug	135
Dalteparin sodium	Anti-coagulant	50
Dexamethasone	Corticosteroid	102
Dexilant	Proton pump inhibitor	68
Dextrose		85
Diazepam	Benzodiazepine	110
Dipyrone		75
Distigmine Bromide		64
Dobutamine	beta-Adrenergic agonist	57
Docusate sodium		54
Doxorubicin	Anthracycline topoisomerase inhibitor	114
Doxorubicin hydrochloride	Anthracycline topoisomerase inhibitor	77
Fentanyl	Opioid agonist	77
Fluorouracil	Nucleoside metabolic inhibitor	87
Fluvoxamine		54
Fragmin	Anti-coagulant	69
Furazolidone		75
Furosemide	Loop diuretic	116
Gabapentin	Anti-epileptic agent	123
Heparin Calcium		53
Heparin sodium	Anti-coagulant	76
Herbals		65
Herbals Paullinia Cupana Seed		61
Humira		113
Hydromorphone		61
Hydromorphone hydrochloride	Opioid agonist	81
Insulin aspart	Insulin analog	67
Ipratropium		52
Ipratropium bromide	Anticholinergic	88
Jardiance	Sodium-Glucose cotransporter 2 inhibitor	59
Keytruda	Programmed death Receptor-1 blocking antibody	241
Lansoprazole	Proton pump inhibitor	90
Lanthanum carbonate	Phosphate binder	75
Magnesium oxide	Calculi dissolution agent	61
Mannitol		52
Melatonin		65
Metformin	Biguanide	52
Methylene blue		59
Metoprolol	beta-Adrenergic blocker	62
Metronidazole	Nitroimidazole antimicrobial	93
Midazolam hydrochloride	Benzodiazepine	50
Nitroglycerin	Nitrate vasodilator	96
Nivolumab	Programmed death Receptor-1 blocking antibody	67
Norepinephrine	Catecholamine	83
Norepinephrine bitartrate	Catecholamine	83
Novorapid		50
Olanzapine	Atypical antipsychotic	126
Ondansetron	Serotonin-3 receptor antagonist	97
Opdivo	Programmed death Receptor-1 blocking antibody	85
Opsumit	Endothelin receptor antagonist	55
Otrivin		66
Oxaliplatin	Platinum-based drug	61
Paclitaxel	Microtubule inhibitor	103
Pantoprazole	Proton pump inhibitor	94
Paroxetine hydrochloride	Serotonin reuptake inhibitor	55
Pembrolizumab	Programmed death Receptor-1 blocking antibody	80
Phytonadione		86
Polyethylene glycol 3350	Osmotic laxative	57
Potassium chloride	Osmotic laxative	67
Prednisone	Corticosteroid	119
Propofol	General anesthetic	81
Quetiapine	Atypical antipsychotic	112
Quetiapine fumarate	Atypical antipsychotic	95
Ramipril	Angiotensin converting enzyme inhibitor	93
Revlimid	Thalidomide analog	69
Rituximab	CD20-directed cytolytic antibody	68
Rocuronium	Nondepolarizing neuromuscular blocker	54
Rosuvastatin	HMG-CoA reductase inhibitor	76
Sevoflurane	General anesthetic	61
Simvastatin	HMG-CoA reductase inhibitor	78
Sodium chloride	Osmotic laxative	71
Sodium citrate	Anti-coagulant	53
Sodium ferric gluconate complex	Parenteral iron replacement	60
Sodium phosphate monobasic		65
Sodium picosulfate		53
Trelegy Ellipta	Anticholinergic	58
Valproate sodium	Anti-epileptic agent	64
Vasopressin		59
Vitamin c	Vitamin C	51
Vitamin K1		65
Warfarin	Vitamin K antagonist	75
Zocor	HMG-CoA reductase inhibitor	61
Zolgensma		103

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 41 pharmacologic classes with 100 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Troponin increased name, in order of name
Class	Reports with this term
Alkylating drug	163
Angiotensin 2 receptor blocker	211
Angiotensin converting enzyme inhibitor	114
Anthracycline topoisomerase inhibitor	213
Anti-coagulant	271
Anti-epileptic agent	236
Antiarrhythmic	118
Anticholinergic	209
Atypical antipsychotic	1,569
Benzodiazepine	371
beta-Adrenergic blocker	186
beta2-Adrenergic agonist	151
Calcium channel blocker	151
Catecholamine	208
Cephalosporin antibacterial	158
Corticosteroid	669
Dihydropyridine calcium channel blocker	109
Endothelin receptor antagonist	101
Erythropoiesis-stimulating agent	105
Factor Xa inhibitor	123
General anesthetic	142
HMG-CoA reductase inhibitor	312
Insulin analog	198
Kinase inhibitor	204
Loop diuretic	145
Microtubule inhibitor	121
Nonsteroidal anti-inflammatory drug	254
Nucleoside metabolic inhibitor	235
Opioid agonist	333
Osmotic laxative	309
P2Y12 platelet inhibitor	120
Phosphate binder	119
Platinum-based drug	272
Programmed death Receptor-1 blocking antibody	532
Proton pump inhibitor	441
Serotonin reuptake inhibitor	219
Serotonin-3 receptor antagonist	123
Thalidomide analog	132
Vitamin C	122
Vitamin K antagonist	112
Xanthine oxidase inhibitor	130

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Troponin increased, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Troponin increased
Age	Reports	Share
Under 2	83	1.1%
2 to 11	34	0.5%
12 to 17	118	1.6%
18 to 44	1,122	15.1%
45 to 64	1,822	24.5%
65 to 74	1,265	17%
75 and over	1,338	18%
Age not given	1,644	22.1%

Sex of the patient in the reports that record Troponin increased
Sex	Reports	Share
Female	3,228	43.5%
Male	3,659	49.3%
Unknown or not given	539	7.3%

Age and sex are as the report gives them. 42.2% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Troponin increased: adverse event reports that record this term. https://reportedreactions.com/reaction/troponin-increased/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 29 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Troponin increased mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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