Paranoia adverse event reports that record this term

Kind of term: MedDRA preferred term
Plain meaning: paranoia

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 17,019 adverse event reports that record the MedDRA preferred term Paranoia. In plain words, the term means: paranoia. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 805 reports in the 12 months to June 2026 and 778 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

By reports in the 12 months to June 2026, this term was number 716 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 805 (0.1%) record this term. Reports for patients aged 18 to 44 were 27.9% of the reports that record this term and 12.3% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Plain meaning

Paranoia. The words are from the fixed dictionary of this site. They add nothing to a report.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 125 drug pages with 50 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Paranoia name as a suspect product, in order of name
Drug	Class	Reports with this term
Abilify	Atypical antipsychotic	366
Abilify Maintena		133
Acetaminophen		73
Adderall	Central nervous system stimulant	120
Alcohol		79
Allopurinol	Xanthine oxidase inhibitor	51
Alprazolam	Benzodiazepine	54
Aripiprazole	Atypical antipsychotic	271
Aristada	Atypical antipsychotic	88
Atazanavir sulfate	Protease inhibitor	102
Atorvastatin		60
Avonex	Interferon beta	82
Baclofen	gamma-Aminobutyric acid-ergic agonist	54
Buprenorphine	Partial opioid agonist	79
Bupropion	Aminoketone	146
Bupropion hydrochloride	Aminoketone	168
Caplyta	Atypical antipsychotic	68
Carbidopa levodopa	Aromatic amino acid	60
Champix		127
Chantix	Partial cholinergic nicotinic agonist	803
Ciprofloxacin	Fluoroquinolone antibacterial	102
Citalopram	Serotonin reuptake inhibitor	208
Citalopram hydrobromide	Serotonin reuptake inhibitor	94
Clarithromycin	Macrolide antimicrobial	121
Clonazepam	Benzodiazepine	285
Clozapine	Atypical antipsychotic	352
Clozaril	Atypical antipsychotic	321
Cocaine		103
Concerta	Central nervous system stimulant	71
Cymbalta		291
Depakote	Anti-epileptic agent	61
Detrol	Cholinergic muscarinic antagonist	51
Dexamethasone	Corticosteroid	96
Diazepam	Benzodiazepine	126
Dilaudid	Opioid agonist	108
Duloxetine	Serotonin and norepinephrine reuptake inhibitor	69
Duodopa		61
Effexor	Serotonin and norepinephrine reuptake inhibitor	79
Enfuvirtide		87
Escitalopram	Serotonin reuptake inhibitor	86
Fentanyl	Opioid agonist	120
Fluoxetine	Serotonin reuptake inhibitor	141
Gabapentin	Anti-epileptic agent	159
Geodon	Atypical antipsychotic	128
Haldol		61
Haloperidol	Typical antipsychotic	90
Humira		93
Hydrocodone bitartrate and acetaminophen	Opioid agonist	115
Invega	Atypical antipsychotic	77
Invega Sustenna	Atypical antipsychotic	276
Invega Trinza	Atypical antipsychotic	95
Isentress	Human immunodeficiency virus integrase strand transfer inhibitor	117
Kaletra	Cytochrome P450 3A inhibitor	103
Keppra		89
Klonopin	Benzodiazepine	55
Lamictal	Anti-epileptic agent	76
Lamivudine	Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	116
Lamotrigine	Anti-epileptic agent	129
Lariam		62
Latuda	Atypical antipsychotic	156
Levaquin		65
Levetiracetam		147
Lexapro	Serotonin reuptake inhibitor	85
Lithium	Mood stabilizer	89
Lorazepam	Benzodiazepine	133
Lyrica		166
Methylphenidate	Central nervous system stimulant	51
Mirtazapine		142
Montelukast	Leukotriene receptor antagonist	118
Morphine sulfate	Opioid agonist	124
MS Contin	Opioid agonist	60
Neurontin		85
Nuplazid	Atypical antipsychotic	617
Olanzapine	Atypical antipsychotic	318
Omeprazole	Proton pump inhibitor	92
Oxycodone and acetaminophen	Opioid agonist	90
Oxycodone hydrochloride	Opioid agonist	259
OxyContin	Opioid agonist	431
Pantoprazole	Proton pump inhibitor	53
Paroxetine	Serotonin reuptake inhibitor	77
Paroxetine hydrochloride	Serotonin reuptake inhibitor	103
Paxil	Serotonin reuptake inhibitor	154
Peg-Intron		55
Pegasys	Interferon alpha	91
Percocet	Opioid agonist	72
Prednisolone	Corticosteroid	52
Prednisone	Corticosteroid	152
Pregabalin		93
Prozac	Serotonin reuptake inhibitor	62
Quetiapine	Atypical antipsychotic	326
Quetiapine fumarate	Atypical antipsychotic	174
Raltegravir potassium		79
Ramipril	Angiotensin converting enzyme inhibitor	51
Ribavirin	Nucleoside analog antiviral	109
Risperdal	Atypical antipsychotic	234
Risperdal Consta		106
Risperidone	Atypical antipsychotic	462
Ritonavir	Cytochrome P450 3A inhibitor	118
Seroquel	Atypical antipsychotic	423
Seroxat		60
Sertraline	Serotonin reuptake inhibitor	371
Sertraline hydrochloride	Serotonin reuptake inhibitor	110
Singulair	Leukotriene receptor antagonist	101
Spravato		53
Strattera	Norepinephrine reuptake inhibitor	76
Suboxone	Opioid antagonist	83
Sustiva		144
Topamax		63
Topiramate		87
Tramadol		87
Trazodone		58
Tysabri	Integrin receptor antagonist	92
Valproate sodium	Anti-epileptic agent	67
Valproic acid	Anti-epileptic agent	132
Venlafaxine	Serotonin and norepinephrine reuptake inhibitor	93
Venlafaxine hydrochloride	Serotonin and norepinephrine reuptake inhibitor	102
Viread	Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	61
Vyvanse	Central nervous system stimulant	160
Wellbutrin	Aminoketone	73
Xanax	Benzodiazepine	112
Xyrem	Central nervous system depressant	217
Xywav	Central nervous system depressant	63
Zoloft	Serotonin reuptake inhibitor	136
Zopiclone		139
Zyprexa	Atypical antipsychotic	179

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 56 pharmacologic classes with 50 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Paranoia name, in order of name
Class	Reports with this term
Alkylating drug	73
Aminoketone	433
Angiotensin converting enzyme inhibitor	81
Anti-epileptic agent	732
Anticholinergic	68
Aromatic amino acid	158
Atypical antipsychotic	5,239
Benzodiazepine	884
beta-Adrenergic blocker	120
CD20-directed cytolytic antibody	90
Central nervous system depressant	311
Central nervous system stimulant	593
Cholinergic muscarinic antagonist	55
Cholinesterase inhibitor	82
Corticosteroid	404
Cytochrome P450 3A inhibitor	252
Dopamine-2 receptor antagonist	90
Factor Xa inhibitor	53
Fluoroquinolone antibacterial	143
gamma-Aminobutyric acid A receptor positive modulator	72
gamma-Aminobutyric acid-ergic agonist	54
GLP-1 receptor agonist	63
Hepatitis B virus nucleoside analog reverse transcriptase inhibitor	202
Histamine-1 receptor antagonist	140
HMG-CoA reductase inhibitor	118
Human immunodeficiency virus integrase strand transfer inhibitor	130
Integrin receptor antagonist	96
Interferon alpha	91
Interferon beta	119
Interleukin-12 antagonist	55
Kinase inhibitor	58
Leukotriene receptor antagonist	265
Macrolide antimicrobial	123
Mood stabilizer	153
Nonergot dopamine agonist	79
Nonsteroidal anti-inflammatory drug	175
Norepinephrine reuptake inhibitor	111
Nucleoside analog antiviral	109
Opioid agonist	1,739
Opioid antagonist	114
Osmotic laxative	94
P2Y12 platelet inhibitor	54
Partial cholinergic nicotinic agonist	817
Partial opioid agonist	106
Phenothiazine	59
Progestin	70
Protease inhibitor	152
Proteasome inhibitor	65
Proton pump inhibitor	240
Serotonin and norepinephrine reuptake inhibitor	475
Serotonin reuptake inhibitor	1,735
Sympathomimetic-like agent	51
Tumor necrosis factor blocker	96
Typical antipsychotic	90
Vesicular monoamine transporter 2 inhibitor	58
Xanthine oxidase inhibitor	51

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Paranoia, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Paranoia
Age	Reports	Share
Under 2	11	0.1%
2 to 11	324	1.9%
12 to 17	389	2.3%
18 to 44	4,756	27.9%
45 to 64	3,531	20.7%
65 to 74	1,064	6.3%
75 and over	873	5.1%
Age not given	6,071	35.7%

Sex of the patient in the reports that record Paranoia
Sex	Reports	Share
Female	8,238	48.4%
Male	7,600	44.7%
Unknown or not given	1,181	6.9%

Age and sex are as the report gives them. 64.1% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Paranoia: adverse event reports that record this term. https://reportedreactions.com/reaction/paranoia/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 29 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Paranoia mean in an adverse event report?

In plain words: paranoia. It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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