MedDRA preferred term · a chaotic rhythm from the lower heart chambers

Ventricular fibrillation: adverse event reports recording this term

10,847 reports to FDA record it, 2004–2026; 0.1% of the database.

Read first · FDA's statement on these data

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product. openFDA, FDA

FDA adds: "There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event." The information in these reports "cannot be used to estimate the incidence of these events."

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

10,847
reports recording the term: 0.1% of all reports; 564
reports, 12 months to June 2026: 474 in the 12 months before; 99.6%
marked serious by the reporter: 57.4% across all reports; 38.2%
record death among outcomes, as reported: 9.1% across all reports

"Ventricular fibrillation" (in plain words, a chaotic rhythm from the lower heart chambers) is a MedDRA preferred term recorded in 10,847 adverse event reports received by FDA, 0.1% of the database, from January 2004 to June 2026. The term is chosen by whoever codes the report to match what the reporter described.

564 reports recorded it in the 12 months to June 2026, up 19% from 474 in the 12 months before. FDA releases FAERS data quarterly, so the newest months are incomplete and grow in later releases. Of reports recording this term, 99.6% are marked serious, 38.2% include death among the outcomes and 57.5% include hospitalisation, as reported.

The drugs listed most often as suspect products in those reports are Ondansetron, Amiodarone and Metronidazole. That order mostly follows how many reports each drug has overall; the table also gives the term's share within each drug's own reports. FDA states that "a causal relationship cannot be established between product and reactions listed in a report" and that for any given report "there is no certainty that a suspected drug caused the event."

Reports by month, five years

FDA releases FAERS data quarterly, so the newest months are incomplete and grow in later releases.

Drugs listed as suspect products in these reports

Drug	Class	Reports with this term	Share of the drug's own reports
Ondansetron	Serotonin-3 receptor antagonist	449	2.6%
Amiodarone	—	380	2.3%
Metronidazole	Nitroimidazole antimicrobial	282	1.2%
Acetaminophen	Nonsteroidal anti-inflammatory drug	275	0.3%
Allopurinol	Xanthine oxidase inhibitor	266	1.2%
Lansoprazole	Proton pump inhibitor	254	1%
Gabapentin	Anti-epileptic agent	253	0.3%
Heparin sodium	Anti-coagulant	253	1.9%
Dextrose	—	249	6.5%
Ipratropium bromide	Anticholinergic	232	2.8%
Simvastatin	HMG-CoA reductase inhibitor	229	0.6%
Amiodarone hydrochloride	Antiarrhythmic	222	4.2%
Melatonin	—	222	5.1%
Phytonadione	—	218	19.3%
Calcitriol	Vitamin D3 analog	216	9.7%
Dobutamine	beta-Adrenergic agonist	213	12.4%
Distigmine Bromide	—	212	67.3%
Lanthanum carbonate	Phosphate binder	212	32.9%
Avandia	—	211	0.2%
Capecitabine	Nucleoside metabolic inhibitor	211	0.4%
Sodium ferric gluconate complex	Parenteral iron replacement	210	50.1%
Betamethasone	—	208	2.9%
Norepinephrine	Catecholamine	206	4.3%
Sodium citrate	Anti-coagulant	204	32.7%
Sodium picosulfate	—	203	17.6%

Drugs with a page on this site, ordered by the number of their reports recording this term. The last column is the term's share within that drug's own reports, against 0.1% across the whole database. FDA states that adverse event reports "represent a small percentage of total usage numbers of a product", that "common products may have a higher number of adverse events due to the higher total number of people using the product", and that the data "by themselves are not an indicator of the safety profile of the drug or biologic."

By pharmacologic class

Class	Reports with this term	Share of class reports	Median drug in class
Corticosteroid	898	0.1%	0%
Anti-coagulant	843	2.9%	1.8%
Osmotic laxative	769	0.6%	0%
Proton pump inhibitor	737	0.2%	0%
Insulin analog	586	0.2%	0%
Nonsteroidal anti-inflammatory drug	524	0.1%	0%
Atypical antipsychotic	517	0.1%	0%
Serotonin-3 receptor antagonist	512	2.3%	1.3%
Nucleoside metabolic inhibitor	490	0.2%	0%
Catecholamine	459	2%	0.8%

Classes ordered by count. Class shares follow the class's overall report volume as much as anything else.

Patients in these reports

Patient age

Under 20.9%103

2 to 111.2%127

12 to 172.2%242

18 to 4419.5%2,115

45 to 6427.8%3,020

65 to 7415.6%1,697

75 and over13.4%1,457

Age not given19.2%2,086

Patient sex

Female39.8%4,319

Male50.7%5,501

Not given9.5%1,027

Grey bar: all 20,646,523 reports in the database. 38.9% of these reports give the United States as the country.

Questions about "Ventricular fibrillation"

What does "Ventricular fibrillation" mean in an adverse event report?

In plain language: a chaotic rhythm from the lower heart chambers. It is a MedDRA preferred term, the dictionary FDA uses to code what a reporter described. The report's own description is not published by openFDA and is not shown here.

How many reports record ventricular fibrillation?

10,847 reports through June 2026 (0.1% of all reports), 564 of them in the latest 12 months.

Which drugs appear most often in these reports?

Ondansetron (449), Amiodarone (380), Metronidazole (282), Acetaminophen (275) and Allopurinol (266). Drugs with many reports overall lead almost every term's list. FDA states that adverse event reports "represent a small percentage of total usage numbers of a product", that "common products may have a higher number of adverse events due to the higher total number of people using the product", and that the data "by themselves are not an indicator of the safety profile of the drug or biologic."

Does a drug appearing here mean it was responsible for this reaction?

No. FDA states that "a causal relationship cannot be established between product and reactions listed in a report" and that for any given report "there is no certainty that a suspected drug caused the event."

I have this symptom. What should I do?

This site cannot assess anyone. A pharmacist or clinician can; for an emergency, call the local emergency number. Nothing on this page is medical advice.

Where this comes from. Counts are built from the openFDA Drug Adverse Event (FAERS) bulk export released 28 Sep 2026, which holds reports FDA received through 30 Jun 2026. Drug names are as reported, resolved to the brand or generic name on the FDA label where openFDA's harmonisation matched them; classes are the pharmacologic class (EPC) from the label and the National Drug Code Directory of 17 Sep 2026. Terms are pooled across spelling and capitalisation variants of one MedDRA preferred term. No report narrative, lot number, patient detail or reporter identity is published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.

Drug data (FAERS) through 30 Jun 2026; device data (MAUDE) through 31 Aug 2026. Not medical advice.