Dissociation adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 7,417 adverse event reports that record the MedDRA preferred term Dissociation. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 1,208 reports in the 12 months to June 2026 and 1,744 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

By reports in the 12 months to June 2026, this term was number 534 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 1,208 (0.1%) record this term. Reports for patients aged 18 to 44 were 38.7% of the reports that record this term and 12.3% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 131 drug pages with 10 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Dissociation name as a suspect product, in order of name
Drug	Class	Reports with this term
Abilify	Atypical antipsychotic	29
Acetaminophen		23
Alcohol		14
Alfuzosin		10
Alprazolam	Benzodiazepine	17
Amiodarone		16
Amitriptyline		53
Amitriptyline hydrochloride	Tricyclic antidepressant	24
Amlodipine	Calcium channel blocker	34
Aripiprazole	Atypical antipsychotic	27
Aspirin	Nonsteroidal anti-inflammatory drug	21
Ativan	Benzodiazepine	12
Auvelity	Aminoketone	70
Avonex	Interferon beta	10
Benztropine	Anticholinergic	22
Bisoprolol	beta-Adrenergic blocker	20
Bisoprolol fumarate	beta-Adrenergic blocker	16
Brexpiprazole	Atypical antipsychotic	13
Bupropion	Aminoketone	12
Bupropion hydrochloride	Aminoketone	36
Caplyta	Atypical antipsychotic	15
Celebrex	Nonsteroidal anti-inflammatory drug	10
Chantix	Partial cholinergic nicotinic agonist	105
Ciprofloxacin	Fluoroquinolone antibacterial	27
Citalopram	Serotonin reuptake inhibitor	69
Clarithromycin	Macrolide antimicrobial	42
Clonazepam	Benzodiazepine	144
Clozapine	Atypical antipsychotic	11
Codeine		39
Codeine phosphate		26
Cymbalta		86
Depakote	Anti-epileptic agent	27
Desvenlafaxine succinate	Serotonin and norepinephrine reuptake inhibitor	12
Dextroamphet Saccharat Amphet Aspartate Dextroamphet Sulfate and Amp		10
Diazepam	Benzodiazepine	104
Digoxin	Cardiac glycoside	32
Disulfiram		10
Domperidone		67
Doxepin	Tricyclic antidepressant	18
Duloxetine	Serotonin and norepinephrine reuptake inhibitor	32
Duloxetine hydrochloride	Serotonin and norepinephrine reuptake inhibitor	12
Effexor	Serotonin and norepinephrine reuptake inhibitor	28
Escitalopram	Serotonin reuptake inhibitor	28
Esketamine		46
Ezetimibe	Dietary cholesterol absorption inhibitor	13
Ezetrol		21
Fetzima	Serotonin and norepinephrine reuptake inhibitor	10
Finasteride	5-alpha reductase inhibitor	13
Fluoxetine	Serotonin reuptake inhibitor	69
Furosemide	Loop diuretic	44
Gabapentin	Anti-epileptic agent	49
Humira		20
Hydrochlorothiazide	Thiazide diuretic	17
Ketamine		38
Klonopin	Benzodiazepine	11
Lacosamide		11
Lamictal	Anti-epileptic agent	48
Lamotrigine	Anti-epileptic agent	35
Lansoprazole	Proton pump inhibitor	30
Latuda	Atypical antipsychotic	27
Levomilnacipran		11
Lexapro	Serotonin reuptake inhibitor	13
Lisdexamfetamine dimesylate	Central nervous system stimulant	17
Lithium	Mood stabilizer	11
Lorazepam	Benzodiazepine	88
Lumryz	Central nervous system depressant	13
Lyrica		88
Melatonin		12
Methylphenidate	Central nervous system stimulant	18
Metronidazole	Nitroimidazole antimicrobial	23
Mianserin		10
Midazolam	Benzodiazepine	11
Mirtazapine		152
Moclobemide		10
Montelukast	Leukotriene receptor antagonist	31
Montelukast sodium	Leukotriene receptor antagonist	11
Morphine	Opioid agonist	10
Neurontin		11
Olanzapine	Atypical antipsychotic	37
Omeprazole	Proton pump inhibitor	71
Oxazepam	Benzodiazepine	10
Oxcarbazepine	Anti-epileptic agent	11
OxyContin	Opioid agonist	12
Paroxetine	Serotonin reuptake inhibitor	97
Paroxetine hydrochloride	Serotonin reuptake inhibitor	89
Paxil	Serotonin reuptake inhibitor	101
Perindopril		23
Phosphorus		49
Pregabalin		26
Procyclidine		43
Procyclidine hydrochloride		19
Quetiapine	Atypical antipsychotic	99
Quetiapine fumarate	Atypical antipsychotic	48
Revlimid	Thalidomide analog	10
Rexulti	Atypical antipsychotic	21
Risperdal	Atypical antipsychotic	11
Risperdal Consta		10
Risperidone	Atypical antipsychotic	11
Seroquel	Atypical antipsychotic	36
Seroxat		38
Sertraline	Serotonin reuptake inhibitor	101
Sertraline hcl	Serotonin reuptake inhibitor	16
Sertraline hydrochloride	Serotonin reuptake inhibitor	15
Singulair	Leukotriene receptor antagonist	20
Sotalol	Antiarrhythmic	13
Spravato		3,733
Strattera	Norepinephrine reuptake inhibitor	10
Subutex		11
Sulpiride		10
Tecfidera		11
Telmisartan	Angiotensin 2 receptor blocker	11
Temazepam	Benzodiazepine	13
Topiramate		21
Tramadol		50
Tramadol hydrochloride	Opioid agonist	28
Trazodone		10
Triazolam	Benzodiazepine	10
Tysabri	Integrin receptor antagonist	37
Valproic acid	Anti-epileptic agent	10
Venlafaxine	Serotonin and norepinephrine reuptake inhibitor	85
Venlafaxine hydrochloride	Serotonin and norepinephrine reuptake inhibitor	20
Vortioxetine		28
Wellbutrin	Aminoketone	15
Xanax	Benzodiazepine	22
Xeplion		10
Xyrem	Central nervous system depressant	20
Zoloft	Serotonin reuptake inhibitor	27
Zolpidem	gamma-Aminobutyric acid A receptor positive modulator	25
Zopiclone		34
Zurzuvae		11
Zyprexa	Atypical antipsychotic	11

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 55 pharmacologic classes with 5 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Dissociation name, in order of name
Class	Reports with this term
5-alpha reductase inhibitor	24
Aminoketone	137
Angiotensin 2 receptor blocker	13
Angiotensin converting enzyme inhibitor	10
Anti-epileptic agent	188
Antiarrhythmic	18
Anticholinergic	25
Antihistamine	13
Aromatic amino acid	5
Atypical antipsychotic	432
Benzodiazepine	447
beta-Adrenergic blocker	36
Calcium channel blocker	37
Cardiac glycoside	32
Central nervous system depressant	37
Central nervous system stimulant	63
Corticosteroid	26
Dietary cholesterol absorption inhibitor	13
Fluoroquinolone antibacterial	30
Folate analog metabolic inhibitor	8
gamma-Aminobutyric acid A receptor positive modulator	31
General anesthetic	10
GLP-1 receptor agonist	24
Hepatitis C virus NS5A inhibitor	5
HMG-CoA reductase inhibitor	14
Integrin receptor antagonist	42
Interferon alpha	5
Interferon beta	12
Kinase inhibitor	8
Leukotriene receptor antagonist	62
Loop diuretic	47
Macrolide antimicrobial	42
Monoamine oxidase inhibitor	6
Mood stabilizer	18
Nitroimidazole antimicrobial	30
Nonergot dopamine agonist	5
Nonsteroidal anti-inflammatory drug	38
Norepinephrine reuptake inhibitor	16
Opioid agonist	95
Orexin receptor antagonist	9
Partial cholinergic nicotinic agonist	109
Penicillin-class antibacterial	6
Progestin	10
Proton pump inhibitor	101
Serotonin and norepinephrine reuptake inhibitor	208
Serotonin reuptake inhibitor	649
Serotonin-1b and Serotonin-1d receptor agonist	8
Soluble guanylate cyclase stimulator	8
Tetracycline-class drug	7
Thalidomide analog	13
Thiazide diuretic	17
Tricyclic antidepressant	53
Tumor necrosis factor blocker	17
Typical antipsychotic	7
Vesicular monoamine transporter 2 inhibitor	5

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Dissociation, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Dissociation
Age	Reports	Share
Under 2	4	0.1%
2 to 11	59	0.8%
12 to 17	87	1.2%
18 to 44	2,873	38.7%
45 to 64	2,068	27.9%
65 to 74	576	7.8%
75 and over	186	2.5%
Age not given	1,564	21.1%

Sex of the patient in the reports that record Dissociation
Sex	Reports	Share
Female	4,535	61.1%
Male	2,347	31.6%
Unknown or not given	535	7.2%

Age and sex are as the report gives them. 72.1% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Dissociation: adverse event reports that record this term. https://reportedreactions.com/reaction/dissociation/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 29 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Dissociation mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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