Decreased interest adverse event reports that record this term
- Kind of term
- MedDRA preferred term
What a report is
A report is not proof that the drug was the cause of the event.
FDA says:
Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on . The data have the reports that FDA received through .
FDA also says:
There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on .
Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on .
Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.
Reports on file
From January 2004 to June 2026, FDA received 5,820 adverse event reports that record the MedDRA preferred term Decreased interest. The person who codes a report selects the term that agrees best with the description of the reporter.
FDA received 198 reports in the 12 months to June 2026 and 254 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.
By reports in the 12 months to June 2026, this term was number 1,325 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 198 (under 0.1%) record this term. Reports for female patients were 58.5% of the reports that record this term and 52.7% of all drug reports.
The number of people who use the product is not in the data. A count is not a rate.
MedDRA
The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.
Data version
openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.
Drugs in these reports
The table has the 132 drug pages with 10 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.
FDA says:
Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on .
Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of . The site read the page on .
| Drug | Class | Reports with this term |
|---|---|---|
| Abilify | Atypical antipsychotic | 43 |
| Acetaminophen Oxycodone Hydrochloride | 12 | |
| Amitriptyline | 11 | |
| Amlodipine | Calcium channel blocker | 31 |
| Ampyra | Potassium channel blocker | 203 |
| Aredia | 140 | |
| Aripiprazole | Atypical antipsychotic | 37 |
| Aspirin | Nonsteroidal anti-inflammatory drug | 23 |
| Aubagio | Pyrimidine synthesis inhibitor | 216 |
| Austedo Xr | 11 | |
| Avonex | Interferon beta | 77 |
| Baclofen | gamma-Aminobutyric acid-ergic agonist | 28 |
| Betaseron | 68 | |
| Bupropion | Aminoketone | 24 |
| Bupropion hydrochloride | Aminoketone | 27 |
| Cabometyx | Kinase inhibitor | 11 |
| Champix | 19 | |
| Chantix | Partial cholinergic nicotinic agonist | 101 |
| Citalopram | Serotonin reuptake inhibitor | 18 |
| Clobetasol propionate | Corticosteroid | 17 |
| Clomipramine | 10 | |
| Clonazepam | Benzodiazepine | 16 |
| Copaxone | 19 | |
| Cosentyx | Interleukin-17A antagonist | 11 |
| Cymbalta | 59 | |
| Desvenlafaxine succinate | Serotonin and norepinephrine reuptake inhibitor | 46 |
| Diazepam | Benzodiazepine | 21 |
| Dilaudid | Opioid agonist | 18 |
| Donepezil | 10 | |
| Duloxetine | Serotonin and norepinephrine reuptake inhibitor | 18 |
| Dupixent | Interleukin-4 receptor alpha antagonist | 116 |
| Effexor | Serotonin and norepinephrine reuptake inhibitor | 122 |
| Enbrel | Tumor necrosis factor blocker | 28 |
| Enoxaparin | 10 | |
| Entresto | Angiotensin 2 receptor blocker | 10 |
| Ergocalciferol | Provitamin D2 compound | 22 |
| Escitalopram | Serotonin reuptake inhibitor | 27 |
| Euthyrox | 45 | |
| Finasteride | 5-alpha reductase inhibitor | 69 |
| Fluoxetine | Serotonin reuptake inhibitor | 17 |
| Flurazepam | 11 | |
| Forteo | Parathyroid hormone analog | 20 |
| Fosamax | Bisphosphonate | 16 |
| Gabapentin | Anti-epileptic agent | 42 |
| Gilenya | Sphingosine 1-phosphate receptor modulator | 344 |
| Humira | 46 | |
| Hydrocodone bitartrate | Opioid agonist | 13 |
| Hydrocodone bitartrate and acetaminophen | Opioid agonist | 37 |
| Hydrocortisone | Corticosteroid | 24 |
| Ibrance | Kinase inhibitor | 12 |
| Invega Sustenna | Atypical antipsychotic | 25 |
| Jakafi | Janus kinase inhibitor | 13 |
| Klonopin | Benzodiazepine | 12 |
| Lamictal | Anti-epileptic agent | 16 |
| Lamotrigine | Anti-epileptic agent | 60 |
| Latuda | Atypical antipsychotic | 22 |
| Lexapro | Serotonin reuptake inhibitor | 19 |
| Lipitor | HMG-CoA reductase inhibitor | 26 |
| Lithium | Mood stabilizer | 18 |
| Lorazepam | Benzodiazepine | 12 |
| Lyrica | 46 | |
| Meloxicam | Nonsteroidal anti-inflammatory drug | 20 |
| Metronidazole | Nitroimidazole antimicrobial | 16 |
| Mirena | Progestin | 28 |
| Mirtazapine | 46 | |
| Moclobemide | 10 | |
| Montelukast | Leukotriene receptor antagonist | 36 |
| Montelukast sodium | Leukotriene receptor antagonist | 10 |
| Morphine sulfate | Opioid agonist | 25 |
| Mounjaro | GLP-1 receptor agonist | 10 |
| MS Contin | Opioid agonist | 16 |
| Myorisan | 25 | |
| Novothyrox | 195 | |
| Nuplazid | Atypical antipsychotic | 25 |
| Ofev | Kinase inhibitor | 15 |
| Omeprazole | Proton pump inhibitor | 17 |
| Otezla | Phosphodiesterase 4 inhibitor | 32 |
| Oxycodone and acetaminophen | Opioid agonist | 30 |
| Oxycodone hydrochloride | Opioid agonist | 89 |
| OxyContin | Opioid agonist | 77 |
| Paroxetine | Serotonin reuptake inhibitor | 23 |
| Paroxetine hydrochloride | Serotonin reuptake inhibitor | 24 |
| Paxil | Serotonin reuptake inhibitor | 30 |
| Pegasys | Interferon alpha | 20 |
| Percocet | Opioid agonist | 16 |
| Pregabalin | 30 | |
| Prolia | RANK ligand inhibitor | 20 |
| Promethazine | Phenothiazine | 10 |
| Propecia | 5-alpha reductase inhibitor | 16 |
| Prozac | Serotonin reuptake inhibitor | 42 |
| Quetiapine | Atypical antipsychotic | 32 |
| Quetiapine fumarate | Atypical antipsychotic | 20 |
| Rebif | Interferon beta | 24 |
| Revlimid | Thalidomide analog | 23 |
| Rexulti | Atypical antipsychotic | 17 |
| Ribavirin | Nucleoside analog antiviral | 25 |
| Risperdal | Atypical antipsychotic | 14 |
| Risperidone | Atypical antipsychotic | 19 |
| Rotigotine | Nonergot dopamine agonist | 32 |
| Seroquel | Atypical antipsychotic | 36 |
| Seroxat | 11 | |
| Sertraline | Serotonin reuptake inhibitor | 46 |
| Singulair | Leukotriene receptor antagonist | 55 |
| Strattera | Norepinephrine reuptake inhibitor | 11 |
| Suboxone | Opioid antagonist | 13 |
| Tecfidera | 147 | |
| Tegretol | Mood stabilizer | 18 |
| Telmisartan | Angiotensin 2 receptor blocker | 20 |
| Temazepam | Benzodiazepine | 11 |
| Teriflunomide | Pyrimidine synthesis inhibitor | 45 |
| Topiramate | 19 | |
| Tramadol | 10 | |
| Tylenol | Expectorant | 23 |
| Tysabri | Integrin receptor antagonist | 52 |
| Venlafaxine | Serotonin and norepinephrine reuptake inhibitor | 30 |
| Venlafaxine hcl | Serotonin and norepinephrine reuptake inhibitor | 11 |
| Venlafaxine hydrochloride | Serotonin and norepinephrine reuptake inhibitor | 27 |
| Viekira Pak | 42 | |
| Vioxx | 10 | |
| Vivitrol | 30 | |
| Vyvanse | Central nervous system stimulant | 11 |
| Wellbutrin | Aminoketone | 16 |
| Xeljanz | Janus kinase inhibitor | 13 |
| Xtandi | Androgen receptor inhibitor | 33 |
| Zantac | 10 | |
| Zepbound | GLP-1 receptor agonist | 10 |
| Zeposia | Sphingosine 1-phosphate receptor modulator | 14 |
| Zoloft | Serotonin reuptake inhibitor | 206 |
| Zolpidem | gamma-Aminobutyric acid A receptor positive modulator | 16 |
| Zometa | 212 | |
| Zopiclone | 11 | |
| Zyprexa | Atypical antipsychotic | 18 |
The page of each drug has the count of each reaction term in its reaction lookup.
Drug classes in these reports
The table has the 54 pharmacologic classes with 10 or more reports that record this term. The rows are in order of name.
FDA says:
Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on .
Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of . The site read the page on .
A class with many reports in all has many reports for almost every term.
Reports by month
FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.
Patients in these reports
| Age | Reports | Share | Share as a bar |
|---|---|---|---|
| Under 2 | 10 | 0.2% | |
| 2 to 11 | 116 | 2% | |
| 12 to 17 | 88 | 1.5% | |
| 18 to 44 | 1,024 | 17.6% | |
| 45 to 64 | 1,357 | 23.3% | |
| 65 to 74 | 521 | 9% | |
| 75 and over | 271 | 4.7% | |
| Age not given | 2,433 | 41.8% |
| Sex | Reports | Share | Share as a bar |
|---|---|---|---|
| Female | 3,403 | 58.5% | |
| Male | 2,053 | 35.3% | |
| Unknown or not given | 364 | 6.3% |
Age and sex are as the report gives them. 73% of these reports give the United States as the country.
Terms near this one
- Death
- Decreased activity
- Decreased appetite
- Decreased immune responsiveness
- Decubitus ulcer
- Deep vein thrombosis
- Defaecation urgency
- Deformity
These are the next terms in the A to Z list. The links are for navigation.
Official pages
- MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
- MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
- FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.
The site checked these addresses on . The links open in a new tab.
Cite this page
Reported Reactions. Decreased interest: adverse event reports that record this term. https://reportedreactions.com/reaction/decreased-interest/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of . Reports received through .
Where the data come from
The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.
The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.
Questions
What does Decreased interest mean in an adverse event report?
It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.
Does a drug in the table mean that the drug was responsible for this reaction?
No. FDA says:
No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on .
When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on .
What does this page tell a person who has this symptom?
This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.
If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on .