Trismus adverse event reports that record this term

Kind of term: MedDRA preferred term

What a report is

A report is not proof that the drug was the cause of the event.

FDA says:

Adverse event reports submitted to FDA do not undergo extensive validation or verification. Therefore, a causal relationship cannot be established between product and reactions listed in a report. While a suspected relationship may exist, it is not medically validated and should not be the sole source of information for clinical decision making or other assumptions about the safety or efficacy of a product. Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview, section "Responsible use of the data". The site read the page on 2 Oct 2026. The data have the reports that FDA received through 30 Jun 2026.

FDA also says:

There is no certainty that the reported event (adverse event or medication error) was actually due to the product. FDA does not require that a causal relationship between a product and event be proven, and reports do not always contain enough detail to properly evaluate an event. The information in these reports has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of these events.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated.
Source: openFDA, Response of the drug event API (meta.disclaimer). The site read the page on 2 Oct 2026.

Not medical advice. This site counts what was reported to FDA. Questions about a medicine or device belong with a pharmacist or clinician.

Reports on file

From January 2004 to June 2026, FDA received 5,089 adverse event reports that record the MedDRA preferred term Trismus. The person who codes a report selects the term that agrees best with the description of the reporter.

FDA received 290 reports in the 12 months to June 2026 and 309 in the 12 months before. FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

By reports in the 12 months to June 2026, this term was number 1,241 of 1,436 reaction terms with a page. Of the 1,332,454 drug reports that FDA received in the 12 months to June 2026, 290 (under 0.1%) record this term. Reports for patients aged 18 to 44 were 23.2% of the reports that record this term and 12.3% of all drug reports.

The number of people who use the product is not in the data. A count is not a rate.

MedDRA

The Medical Dictionary for Regulatory Activities. The person who codes a report selects the preferred term that agrees best with the description of the reporter. FDA does not publish the description.

Data version

openFDA FAERS release of 29 Oct 2026. Reports received through 30 Jun 2026.

Drugs in these reports

The table has the 146 drug pages with 10 or more reports that record this term. The rows are in order of name. A drug page with fewer reports for this term is not in the table. The counts are the counts that the site keeps for each reaction term, and a count can be lower than the count of FDA.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Drugs that the reports with the term Trismus name as a suspect product, in order of name
Drug	Class	Reports with this term
Abilify	Atypical antipsychotic	103
Abilify Maintena		20
Actonel	Bisphosphonate	13
Alemtuzumab	CD52-directed cytolytic antibody	10
Alendronate sodium	Bisphosphonate	16
Alendronic Acid		14
Ambrisentan	Endothelin receptor antagonist	12
Amfetamine		15
Aredia		25
Aripiprazole	Atypical antipsychotic	102
Atomoxetine	Norepinephrine reuptake inhibitor	19
Atorvastatin calcium	HMG-CoA reductase inhibitor	12
Austedo		20
Avastin	Vascular endothelial growth factor inhibitor	14
Avonex	Interferon beta	13
Benztropine mesylate	Anticholinergic	36
Boniva		15
Botox	Acetylcholine release inhibitor	48
Cabometyx	Kinase inhibitor	14
Capecitabine	Nucleoside metabolic inhibitor	29
Carbamazepine	Mood stabilizer	30
Carbidopa levodopa	Aromatic amino acid	11
Carboplatin	Platinum-based drug	37
Chlorpromazine	Phenothiazine	23
Cilastatin Sodium Imipenem		15
Cimzia	Tumor necrosis factor blocker	12
Cisplatin	Platinum-based drug	35
Citalopram	Serotonin reuptake inhibitor	44
Citalopram hydrobromide	Serotonin reuptake inhibitor	11
Clarithromycin	Macrolide antimicrobial	25
Clonazepam	Benzodiazepine	23
Clonidine	Central alpha-2 adrenergic agonist	31
Clozapine	Atypical antipsychotic	22
Concerta	Central nervous system stimulant	22
Cosentyx	Interleukin-17A antagonist	29
Cyclophosphamide	Alkylating drug	29
Cyclosporine	Calcineurin inhibitor immunosuppressant	10
Cymbalta		46
Cytarabine	Nucleoside metabolic inhibitor	11
Dactinomycin		12
Depakine		15
Depakine Chrono		23
Depakote	Anti-epileptic agent	14
Dexamethasone	Corticosteroid	11
Diazepam	Benzodiazepine	23
Docetaxel	Microtubule inhibitor	13
Duloxetine	Serotonin and norepinephrine reuptake inhibitor	16
Dupixent	Interleukin-4 receptor alpha antagonist	36
Enbrel	Tumor necrosis factor blocker	47
Escitalopram	Serotonin reuptake inhibitor	52
Etoposide	Topoisomerase inhibitor	16
Fentanyl	Opioid agonist	14
Fluorouracil	Nucleoside metabolic inhibitor	21
Fluoxetine	Serotonin reuptake inhibitor	31
Forteo	Parathyroid hormone analog	17
Fosamax	Bisphosphonate	124
Fosamax Plus D		10
Gabapentin	Anti-epileptic agent	79
Geodon	Atypical antipsychotic	35
Haldol		32
Haloperidol	Typical antipsychotic	35
Humira		94
Ibuprofen	Nonsteroidal anti-inflammatory drug	18
Imipramine		15
Ingrezza	Vesicular monoamine transporter 2 inhibitor	27
Invega	Atypical antipsychotic	34
Invega Sustenna	Atypical antipsychotic	26
Irinotecan		25
Lamictal	Anti-epileptic agent	25
Lamotrigine	Anti-epileptic agent	13
Latuda	Atypical antipsychotic	74
Leflunomide	Antirheumatic agent	14
Levetiracetam		21
Lidocaine	Amide local anesthetic	15
Lisdexamfetamine	Central nervous system stimulant	20
Lithium	Mood stabilizer	40
Lorazepam	Benzodiazepine	12
Loxapine		14
Lyrica		16
Methadone	Opioid agonist	25
Methotrexate	Folate analog metabolic inhibitor	49
Methylphenidate	Central nervous system stimulant	26
Methylphenidate hydrochloride	Central nervous system stimulant	30
Metoclopramide	Dopamine-2 receptor antagonist	31
Mirtazapine		21
Modafinil	Sympathomimetic-like agent	17
Morphine	Opioid agonist	18
Nortriptyline		41
Olanzapine	Atypical antipsychotic	27
Ondansetron	Serotonin-3 receptor antagonist	28
Opsumit	Endothelin receptor antagonist	11
Orenitram	Prostacycline vasodilator	18
Oxaliplatin	Platinum-based drug	67
Paroxetine	Serotonin reuptake inhibitor	17
Paroxetine hydrochloride	Serotonin reuptake inhibitor	16
Paxil	Serotonin reuptake inhibitor	18
Phenytoin	Anti-epileptic agent	12
Plaquenil	Antimalarial	12
Prednisolone	Corticosteroid	11
Prednisone	Corticosteroid	27
Pregabalin		16
Prolia	RANK ligand inhibitor	112
Propofol	General anesthetic	19
Quetiapine	Atypical antipsychotic	95
Quetiapine fumarate	Atypical antipsychotic	18
Rabeprazole	Proton pump inhibitor	42
Reclast	Bisphosphonate	12
Remicade	Tumor necrosis factor blocker	74
Remodulin	Prostacycline vasodilator	16
Revlimid	Thalidomide analog	25
Rexulti	Atypical antipsychotic	16
Rinvoq	Janus kinase inhibitor	11
Risperdal	Atypical antipsychotic	42
Risperidone	Atypical antipsychotic	44
Rituximab	CD20-directed cytolytic antibody	15
Seroquel	Atypical antipsychotic	59
Sertraline	Serotonin reuptake inhibitor	127
Sertraline hcl	Serotonin reuptake inhibitor	11
Sertraline hydrochloride	Serotonin reuptake inhibitor	17
Sinemet	Aromatic amino acid	12
Soliris	Complement inhibitor	10
Sulfasalazine	Aminosalicylate	13
Sumatriptan	Serotonin-1b and Serotonin-1d receptor agonist	12
Tecfidera		10
Tegretol	Mood stabilizer	14
Thiotepa	Alkylating drug	14
Tramadol		21
Tymlos		13
Tysabri	Integrin receptor antagonist	27
Tyvaso	Prostacycline vasodilator	10
Uptravi	Prostacyclin receptor agonist	30
Valproic acid	Anti-epileptic agent	27
Veletri	Prostacycline vasodilator	14
Venlafaxine	Serotonin and norepinephrine reuptake inhibitor	19
Venlafaxine hydrochloride	Serotonin and norepinephrine reuptake inhibitor	17
Vincristine		23
Vraylar	Atypical antipsychotic	12
Vyvanse	Central nervous system stimulant	12
Xyrem	Central nervous system depressant	12
Ziprasidone	Atypical antipsychotic	25
Zoledronic acid	Bisphosphonate	27
Zoloft	Serotonin reuptake inhibitor	12
Zolpidem	gamma-Aminobutyric acid A receptor positive modulator	12
Zometa		75
Zopiclone		45
Zyprexa	Atypical antipsychotic	30

The page of each drug has the count of each reaction term in its reaction lookup.

Drug classes in these reports

The table has the 40 pharmacologic classes with 25 or more reports that record this term. The rows are in order of name.

FDA says:

Additionally, it is important to remember that adverse event reports represent a small percentage of total usage numbers of a product. Common products may have a higher number of adverse events due to the higher total number of people using the product.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

Importantly, the AEMS data by themselves are not an indicator of the safety profile of the drug or biologic.
Source: FDA, FDA Adverse Event Monitoring System (AEMS) Public Dashboard. Content current as of 11 Mar 2026. The site read the page on 2 Oct 2026.

Pharmacologic classes of the drugs that the reports with the term Trismus name, in order of name
Class	Reports with this term
Acetylcholine release inhibitor	64
Alkylating drug	47
Anti-epileptic agent	172
Anticholinergic	47
Aromatic amino acid	32
Atypical antipsychotic	792
Benzodiazepine	84
Bisphosphonate	196
CD20-directed cytolytic antibody	37
Central alpha-2 adrenergic agonist	33
Central nervous system stimulant	138
Corticosteroid	82
Dopamine-2 receptor antagonist	41
Endothelin receptor antagonist	30
Folate analog metabolic inhibitor	67
General anesthetic	27
HMG-CoA reductase inhibitor	28
Integrin receptor antagonist	27
Interleukin-17A antagonist	29
Interleukin-4 receptor alpha antagonist	36
Kinase inhibitor	49
Macrolide antimicrobial	25
Mood stabilizer	84
Nonsteroidal anti-inflammatory drug	35
Nucleoside metabolic inhibitor	74
Opioid agonist	90
Phenothiazine	28
Platinum-based drug	139
Prostacyclin receptor agonist	30
Prostacycline vasodilator	58
Proton pump inhibitor	59
RANK ligand inhibitor	130
Serotonin and norepinephrine reuptake inhibitor	72
Serotonin reuptake inhibitor	376
Serotonin-1b and Serotonin-1d receptor agonist	25
Serotonin-3 receptor antagonist	28
Thalidomide analog	29
Tumor necrosis factor blocker	156
Typical antipsychotic	37
Vesicular monoamine transporter 2 inhibitor	32

A class with many reports in all has many reports for almost every term.

Reports by month

Reports that record Trismus, by month, five years to June 2026

FDA releases FAERS data every quarter, so the newest months are not complete. They grow in later releases.

Patients in these reports

Age of the patient in the reports that record Trismus
Age	Reports	Share
Under 2	51	1%
2 to 11	180	3.5%
12 to 17	156	3.1%
18 to 44	1,180	23.2%
45 to 64	1,202	23.6%
65 to 74	481	9.5%
75 and over	333	6.5%
Age not given	1,506	29.6%

Sex of the patient in the reports that record Trismus
Sex	Reports	Share
Female	3,076	60.4%
Male	1,571	30.9%
Unknown or not given	442	8.7%

Age and sex are as the report gives them. 50.3% of these reports give the United States as the country.

Terms near this one

These are the next terms in the A to Z list. The links are for navigation.

Official pages

MedWatch Online Voluntary Reporting FormThe online form of FDA for a voluntary report.
MedWatch: The FDA Safety Information and Adverse Event Reporting ProgramThe page of the FDA program that receives reports about drugs and devices.
FDA Adverse Event Monitoring System (AEMS) Public DashboardThe public dashboard of FDA for adverse event reports on drugs and biologics.

The site checked these addresses on 2 Oct 2026. The links open in a new tab.

Cite this page

Reported Reactions. Trismus: adverse event reports that record this term. https://reportedreactions.com/reaction/trismus/ Source: U.S. Food and Drug Administration, openFDA Drug Adverse Event (FAERS) files, release of 29 Oct 2026. Reports received through 30 Jun 2026.

Where the data come from

The counts come from the openFDA Drug Adverse Event (FAERS) bulk files, release of 29 Oct 2026. The files have the reports that FDA received through 30 Jun 2026. A drug name is the name on the report. The site matches it to a brand name or a generic name of the National Drug Code Directory of 2 Nov 2026. A class is the pharmacologic class (EPC) of the FDA label.

The count has the reports with each spelling of one MedDRA preferred term. The site does not publish a report narrative, a lot number, a detail of a patient or the identity of a reporter. The record of FDA is the authority. See how the site counts reports, the data sources and the corrections page.

Questions

What does Trismus mean in an adverse event report?

It is a MedDRA preferred term. FDA codes the description of a reporter with the MedDRA dictionary. The openFDA files do not have the description itself, and this site does not show it.

Does a drug in the table mean that the drug was responsible for this reaction?

No. FDA says:

No individual drug is connected to any individual reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

When a report lists multiple drugs and multiple reactions, there is no way to conclude from the data therein that a given drug is responsible for a given reaction.
Source: openFDA, Drug Adverse Event Overview. The site read the page on 2 Oct 2026.

What does this page tell a person who has this symptom?

This page gives counts of reports. It cannot assess a person. A pharmacist or a clinician can assess a person.

If this is a medical emergency, please call 911.
Source: FDA, MedWatch Online Voluntary Reporting Form. The site read the page on 2 Oct 2026.

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